Reptile · Centrochelys sulcata · typical adult weight 1.00–40.00 kg
Itraconazole is dosed at 5 mg/kg PO q24h in sulcata tortoises, per Martel A, Hellebuyck T, Van Waeyenberghe L. Treatment of infections with Nannizziopsis vriesii, an emergent reptilian dermatophyte. Proc Annu Conf Assoc Rept Amph Vet; 2009:69-70. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.222 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.3 (Antifungal Agents Used in Reptiles). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Itraconazole is used in sulcata tortoises for Systemic/cutaneous mycosis. Routes documented in sulcata tortoises: PO. A typical adult sulcata tortoise weighs 1.00–40.00 kg. ExoticRx lists 1 cited dose rule for Itraconazole in sulcata tortoises, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Sporanox, Itrafungol
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 5 mg/kg | q24h | Systemic/cutaneous mycosis | Weak | Martel A, Hellebuyck T, Van Waeyenberghe L. Treatment of infections with Nannizziopsis vriesii, an emergent reptilian dermatophyte. Proc Annu Conf Assoc Rept Amph Vet; 2009:69-70. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.222 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.3 (Antifungal Agents Used in Reptiles). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (%) | Route | Source | As printed |
|---|---|---|---|
| 1 | TOPICAL | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | mg/kg PO q24h52 01% in 0.6% salt solution x 5 min bath q24h × 1 01% in buffered solution x 5 min bath q24h × 11 days16 Topical route best choice to treat chytridiomycosis; caution |
| 0.6 | TOPICAL | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | mg/kg PO q24h52 01% in 0.6% salt solution x 5 min bath q24h × 1 01% in buffered solution x 5 min bath q24h × 11 days16 Topical route best choice to treat chytridiomycosis; caution |
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 5–10 | PO | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets) |
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These ranges are per kg. Enter your sulcata tortoise's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits fungal 14-alpha-demethylase, blocking ergosterol synthesis. Lipophilic with high tissue concentrations.
Hepatotoxic: monitor liver enzymes. Requires acid pH for capsule absorption (give with food). Negative inotropic effect — avoid in animals with heart failure. CYP3A4 inhibitor.
Species-specific contraindications and adverse-reaction reports for sulcata tortoises may differ from canine / feline reference data — consult the primary citations listed with each rule.
Itraconazole dose range in sulcata tortoises, with cited source references: PO 5 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Itraconazole in sulcata tortoises: PO.
Itraconazole is indicated in sulcata tortoises for: Systemic/cutaneous mycosis.
These are general warnings for Itraconazole across species; consult the sulcata tortoise dosing table above for species-specific guidance. Hepatotoxic: monitor liver enzymes. Requires acid pH for capsule absorption (give with food). Negative inotropic effect — avoid in animals with heart failure. CYP3A4 inhibitor.
Why a species-specific page? Itraconazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in sulcata tortoises — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 5-10 mg/kg p.o. q24h (most species). Metabolically scaled doses have been suggested for the treatme |
| 5 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 4.3 | 5 mg/kg PO q24h |
| 5 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.3 | 5 mg/kg SC184 Cottonmouths/deaths in 3 out of 4 animals; not recommended |
| 5 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.3 | 5 mg/kg PO q24h214 Most species/some hepatotoxicity noted when used for Chrysosporium anamorph of Nannizziopsis vriesii; can cause anorexia in bearded dragons without evidence of h |
| Dose (mg/l) | Route | Source | As printed |
|---|---|---|---|
| 15 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | 5-1.5 mg/L × 5 min bath q24h × 7 days15 mg/L x 5 min bath q24h × 10 days22 Alytes muletensis tadpoles/safe at varying concentrations and duration of 7-28 days; confirmed negative P |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.