Reptile · Centrochelys sulcata · typical adult weight 1.00–40.00 kg
Amphotericin B is dosed at 0.5 mg/kg IV q48-72h in sulcata tortoises, per Carpenter JW, Klaphake E, Gibbons PM, et al. Reptile formulary. In: Divers SJ, Stahl SJ, eds. Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed., Elsevier, St. Louis, MO; 2019:1191-1211. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.221 (2026-08-01, PENDING REVIEW). Amphotericin B is used in sulcata tortoises for Systemic mycosis. Routes documented in sulcata tortoises: IV. A typical adult sulcata tortoise weighs 1.00–40.00 kg. ExoticRx lists 1 cited dose rule for Amphotericin B in sulcata tortoises, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Fungizone, Abelcet
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IV | 0.5 mg/kg | q48-72h | Systemic mycosis | Weak | Carpenter JW, Klaphake E, Gibbons PM, et al. Reptile formulary. In: Divers SJ, Stahl SJ, eds. Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed., Elsevier, St. Louis, MO; 2019:1191-1211. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.221 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your sulcata tortoise's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds ergosterol in fungal cell membranes, creating pores that cause leakage of intracellular contents and cell death.
Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Species-specific contraindications and adverse-reaction reports for sulcata tortoises may differ from canine / feline reference data — consult the primary citations listed with each rule.
Amphotericin B dose range in sulcata tortoises, with cited source references: IV 0.5 mg/kg q48-72h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Amphotericin B in sulcata tortoises: IV.
Amphotericin B is indicated in sulcata tortoises for: Systemic mycosis.
These are general warnings for Amphotericin B across species; consult the sulcata tortoise dosing table above for species-specific guidance. Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Why a species-specific page? Amphotericin B pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in sulcata tortoises — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.