Reptile · Eublepharis macularius · typical adult weight 0.04–0.10 kg
Fluconazole is dosed at 5 mg/kg PO q24h in leopard geckos, per 345. Wissman MA, Parsons B. Dermatophytosis of green iguanas (Iguana iguana). J Small Exot Anim Med. 1993;2:133-136. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1404 (2026-08-01, PENDING REVIEW). Fluconazole is used in leopard geckos for Dermatophytosis. Routes documented in leopard geckos: PO. A typical adult leopard gecko weighs 0.04–0.10 kg. ExoticRx lists 1 cited dose rule for Fluconazole in leopard geckos, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Diflucan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 5 mg/kg | q24h | Dermatophytosis | Weak | 345. Wissman MA, Parsons B. Dermatophytosis of green iguanas (Iguana iguana). J Small Exot Anim Med. 1993;2:133-136. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1404 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your leopard gecko's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits fungal cytochrome P450 enzyme 14-alpha-demethylase, blocking ergosterol synthesis and disrupting fungal cell membrane.
Hepatotoxic: monitor liver enzymes during prolonged therapy. Drug interactions via CYP450 inhibition. Good CNS and ocular penetration.
Species-specific contraindications and adverse-reaction reports for leopard geckos may differ from canine / feline reference data — consult the primary citations listed with each rule.
Fluconazole dose range in leopard geckos, with cited source references: PO 5 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Fluconazole in leopard geckos: PO.
Fluconazole is indicated in leopard geckos for: Dermatophytosis.
These are general warnings for Fluconazole across species; consult the leopard gecko dosing table above for species-specific guidance. Hepatotoxic: monitor liver enzymes during prolonged therapy. Drug interactions via CYP450 inhibition. Good CNS and ocular penetration.
Why a species-specific page? Fluconazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in leopard geckos — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.