Reptile · Terrapene carolina · typical adult weight 0.30–0.60 kg
Ketoconazole is dosed at 15 mg/kg PO q72h in eastern box turtles, per 149. Jepson L. Lizards. Exotic Animal Medicine: A Quick Reference Guide. Philadelphia: Saunders/Elsevier; 2009:268-314. | 150. Jepson L. Snakes. Exotic Animal Medicine: A Quick Reference Guide. Philadelphia: Saunders/Elsevier; 2009:315-357. | 151. Jepson L. Turtles and tortoises. Exotic Animal Medicine: A Quick Reference Guide. Philadelphia: Saunders/Elsevier; 2009:358-411. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1405 (2026-08-01, PENDING REVIEW). Ketoconazole is used in eastern box turtles for mycosis. Routes documented in eastern box turtles: PO. A typical adult eastern box turtle weighs 0.30–0.60 kg. ExoticRx lists 1 cited dose rule for Ketoconazole in eastern box turtles, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Nizoral
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 15 mg/kg | q72h | mycosis | Weak | 149. Jepson L. Lizards. Exotic Animal Medicine: A Quick Reference Guide. Philadelphia: Saunders/Elsevier; 2009:268-314. | 150. Jepson L. Snakes. Exotic Animal Medicine: A Quick Reference Guide. Philadelphia: Saunders/Elsevier; 2009:315-357. | 151. Jepson L. Turtles and tortoises. Exotic Animal Medicine: A Quick Reference Guide. Philadelphia: Saunders/Elsevier; 2009:358-411. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1405 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your eastern box turtle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits lanosterol 14-alpha-demethylase (CYP51), blocking ergosterol synthesis in fungal membranes. At high doses, inhibits adrenal and gonadal steroidogenesis.
Hepatotoxic — monitor liver enzymes. Strong CYP inhibitor (many drug interactions). Requires gastric acid for absorption (do not give with antacids). Also used for Cushing's disease (adrenal steroidogenesis inhibition).
Species-specific contraindications and adverse-reaction reports for eastern box turtles may differ from canine / feline reference data — consult the primary citations listed with each rule.
Ketoconazole dose range in eastern box turtles, with cited source references: PO 15 mg/kg q72h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Ketoconazole in eastern box turtles: PO.
Ketoconazole is indicated in eastern box turtles for: mycosis.
These are general warnings for Ketoconazole across species; consult the eastern box turtle dosing table above for species-specific guidance. Hepatotoxic — monitor liver enzymes. Strong CYP inhibitor (many drug interactions). Requires gastric acid for absorption (do not give with antacids). Also used for Cushing's disease (adrenal steroidogenesis inhibition).
Why a species-specific page? Ketoconazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in eastern box turtles — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.