Reptile · Python regius · typical adult weight 1.00–2.00 kg
Ketoconazole is dosed at 25 mg/kg PO q24h in ball pythons, per Jacobson ER. Antimicrobial drug use in reptiles. In: Prescott JF, Baggot JD, eds. Antimicrobial Therapy in Veterinary Medicine; Iowa State University Press, Ames, IA; 1993:543-552. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.222 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.3 (Antifungal Agents Used in Reptiles). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Ketoconazole is used in ball pythons for Systemic/cutaneous mycosis. Routes documented in ball pythons: PO. A typical adult ball python weighs 1.00–2.00 kg. ExoticRx lists 1 cited dose rule for Ketoconazole in ball pythons, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Nizoral
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 25 mg/kg | q24h | Systemic/cutaneous mycosis | Weak |
| Jacobson ER. Antimicrobial drug use in reptiles. In: Prescott JF, Baggot JD, eds. Antimicrobial Therapy in Veterinary Medicine; Iowa State University Press, Ames, IA; 1993:543-552. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.222 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.3 (Antifungal Agents Used in Reptiles). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 15 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 4.3 | 15 mg/kg q72h PO,222,243 |
| 25 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 4.3 | 25 mg/kg PO q24h × 21 days |
| 15 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.3 | 15 mg/kg q72h PO149-151 Most species |
| 25 | PO |
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Inhibits lanosterol 14-alpha-demethylase (CYP51), blocking ergosterol synthesis in fungal membranes. At high doses, inhibits adrenal and gonadal steroidogenesis.
Hepatotoxic — monitor liver enzymes. Strong CYP inhibitor (many drug interactions). Requires gastric acid for absorption (do not give with antacids). Also used for Cushing's disease (adrenal steroidogenesis inhibition).
Species-specific contraindications and adverse-reaction reports for ball pythons may differ from canine / feline reference data — consult the primary citations listed with each rule.
Ketoconazole dose range in ball pythons, with cited source references: PO 25 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Ketoconazole in ball pythons: PO.
Ketoconazole is indicated in ball pythons for: Systemic/cutaneous mycosis.
These are general warnings for Ketoconazole across species; consult the ball python dosing table above for species-specific guidance. Hepatotoxic — monitor liver enzymes. Strong CYP inhibitor (many drug interactions). Requires gastric acid for absorption (do not give with antacids). Also used for Cushing's disease (adrenal steroidogenesis inhibition).
Why a species-specific page? Ketoconazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in ball pythons — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 25 mg/kg PO q24h × 21 days144 Snakes, turtles |
| 50 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.3 | 50 mg/kg PO q24h × 14-28 days99 Crocodilians |
| 10–20 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.2 | 10-20 mg/kg PO q24h52 Topical cream52 |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.