Pocket Pet · Mus musculus · typical adult weight 0.02–0.04 kg
Amphotericin B is dosed at 0.43 mg/kg PO q24h in mice, per 122. Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015.; 130. Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.770 (2026-08-01, PENDING REVIEW). Amphotericin B is used in mice for Candidiasis, Systemic mycosis. Routes documented in mice: PO, SC. A typical adult mouse weighs 0.02–0.04 kg. ExoticRx lists 2 cited dose rules for Amphotericin B in mice, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Fungizone, Abelcet
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 0.43 mg/kg | q24h | Candidiasis | Moderate | 122. Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015.; 130. Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.770 (2026-08-01, PENDING REVIEW) |
| SC | 0.11 mg/kg | q24h | Systemic mycosis | Moderate | 122. Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015.; 130. Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.770 (2026-08-01, PENDING REVIEW) |
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Binds ergosterol in fungal cell membranes, creating pores that cause leakage of intracellular contents and cell death.
Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Species-specific contraindications and adverse-reaction reports for mice may differ from canine / feline reference data — consult the primary citations listed with each rule.
Amphotericin B dose ranges in mice, with cited source references: PO 0.43 mg/kg q24h; SC 0.11 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Amphotericin B in mice: PO, SC.
Amphotericin B is indicated in mice for: Candidiasis, Systemic mycosis.
These are general warnings for Amphotericin B across species; consult the mouse dosing table above for species-specific guidance. Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Why a species-specific page? Amphotericin B pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in mice — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.