Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Bupivacaine is dosed at 1–2 mg/kg Local once per procedure in rabbits, per Hawkins MG. Advances in exotic mammal clinical therapeutics. J Exot Pet Med. 2014;23:39-49. doi:10.1053/j.jepm.2013.11.006; Scarabelli S. Loco-regional anesthesia in rabbits. Proc Conf Annu Assoc Exot Mam Vet; 2019:444-452. PMID: 37627351; Lennox AM. Anesthesia and analgesia for critical exotic companion mammals. Proc Internat Vet Emer Crit Care Symp; 2015. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.856 (2026-08-01).. Bupivacaine is used in rabbits for Local anesthesia. Routes documented in rabbits: Local. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Bupivacaine in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Marcaine, Nocita
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Local | 1–2 mg/kg | once per procedure | Duration 4-8 hours | Local anesthesia |
| Hawkins MG. Advances in exotic mammal clinical therapeutics. J Exot Pet Med. 2014;23:39-49. doi:10.1053/j.jepm.2013.11.006; Scarabelli S. Loco-regional anesthesia in rabbits. Proc Conf Annu Assoc Exot Mam Vet; 2019:444-452. PMID: 37627351; Lennox AM. Anesthesia and analgesia for critical exotic companion mammals. Proc Internat Vet Emer Crit Care Symp; 2015. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.856 (2026-08-01). |
Need the exact dose for your patient?
These ranges are per kg. Enter your rabbit's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Long-acting amide local anesthetic blocking voltage-gated sodium channels. Duration 4-8 hours (standard) or 72 hours (Nocita liposomal).
Nocita (liposomal bupivacaine) FDA-approved for post-op pain in dogs/cats. Cardiotoxic if inadvertently given IV. Do not use with epinephrine on digits/tail.
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Bupivacaine dose range in rabbits, with cited source references: Local 1–2 mg/kg once per procedure. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Bupivacaine in rabbits: Local.
Cited course lengths for Bupivacaine in rabbits include: Duration 4-8 hours. Duration depends on the indication — match it to the specific dose rule in the table above.
Bupivacaine is indicated in rabbits for: Local anesthesia.
These are general warnings for Bupivacaine across species; consult the rabbit dosing table above for species-specific guidance. Nocita (liposomal bupivacaine) FDA-approved for post-op pain in dogs/cats. Cardiotoxic if inadvertently given IV. Do not use with epinephrine on digits/tail.
Why a species-specific page? Bupivacaine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.