ExoticRx · exoticrx.com/drugs/bupivacaine
Bupivacaine
Marcaine, Nocita(liposomal)
Drug Class
Routes
Indications
Mechanism of Action
Long-acting amide local anesthetic blocking voltage-gated sodium channels. Duration 4-8 hours (standard) or 72 hours (Nocita liposomal).
Side effects & warnings
Nocita (liposomal bupivacaine) FDA-approved for post-op pain in dogs/cats. Cardiotoxic if inadvertently given IV. Do not use with epinephrine on digits/tail.
Species with Bupivacaine dosing data (4 dose rules)
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugsAll Guinea Pig drugsAll Rabbit (Domestic) drugs
Evidence levels across 4 dose rules
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Backed by 2 published sources
- · Carpenter's Exotic Animal Formulary, 6th Ed
- · Plumb's Veterinary Drug Handbook, 9th Ed
Sample dosing (2 of 4 cited rules)
A dog/cat sample is shown here. Cited dosing for all 4 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
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View PlansArticles mentioning Bupivacaine
- Avian Aspergillosis: Voriconazole vs Itraconazole ProtocolsWhen to reach for voriconazole instead of itraconazole in psittacine aspergillosis — and why the choice matters more in African Greys.
- Anesthesia in Exotic Companion Animals: A Practical OverviewInhalational and injectable anesthesia choices for rabbits, guinea pigs, parrots, and reptiles — and what species-specific physiology should change in your protocol.
More Neurological drugs
Source citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.