ExoticRx · exoticrx.com/drugs/carbidopa-levodopa
US brand names:Sinemet
Carbidopa-Levodopa is dosed at 1–3 mg/kg PO q8h-q12h (levodopa component) in cats, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Levodopa is converted to dopamine in the CNS. Carbidopa inhibits peripheral DOPA decarboxylase, reducing peripheral side effects and increasing CNS levodopa availability.
GI upset common. May cause behavioral changes, dyskinesia. Very limited veterinary use — primarily investigational for movement disorders.
Species references:All Cat (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | PO | 1–3 mg/kg | q8h-q12h (levodopa component) | Anecdotal | Plumb's Veterinary Drug Handbook, 9th Ed |
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.