Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Difloxacin is dosed at 5 mg/kg IM, IV q24h in rabbits, per Abd El-Aty AM, Goudah A, Ismail M, et al. Disposition kinetics of difloxacin in rabbits after intravenous and intramuscular injection of Dicural. Vet Res Commun. 2005;29:297-304. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.842 (2026-08-01, PENDING REVIEW). Difloxacin is used in rabbits for E. coli infections. Routes documented in rabbits: IM, IV. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Difloxacin in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Dicural
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM, IV | 5 mg/kg | q24h | E. coli infections | Weak | Abd El-Aty AM, Goudah A, Ismail M, et al. Disposition kinetics of difloxacin in rabbits after intravenous and intramuscular injection of Dicural. Vet Res Commun. 2005;29:297-304. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.842 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your rabbit's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits bacterial DNA gyrase and topoisomerase IV. Concentration-dependent bactericidal activity.
Avoid in growing animals (cartilage damage). May lower seizure threshold. Primarily approved for dogs.
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Difloxacin dose range in rabbits, with cited source references: IM, IV 5 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Difloxacin in rabbits: IM, IV.
Difloxacin is indicated in rabbits for: E. coli infections.
These are general warnings for Difloxacin across species; consult the rabbit dosing table above for species-specific guidance. Avoid in growing animals (cartilage damage). May lower seizure threshold. Primarily approved for dogs.
Why a species-specific page? Difloxacin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.