Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Prednisone is dosed at 0.5–2 mg/kg PO q12-24h in rabbits, per Andres K, Kent M, Seidlecki C, et al. The use of megavoltage radiation therapy in the treatment of thymoma in rabbits: 19 cases. Vet Comp Oncol. 2012;10:82-94. | Donnelly TM. Rabbit with cutaneous lymphoma: chemotherapy options and drug doses. VIN Vet-to-Vet Message Boards. www.vin.com. | Heatley JJ, Smith AN. Spontaneous neoplasms of lagomorphs. Vet Clin North Am Exot Anim Pract. 2004;7:561-577. | Perez K, Chen S, Antinoff N. Use of prednisolone in six rabbits (Oryctolagus cuniculus) with cranial mediastinal disease. Proc Conf Annu Assoc Exot Mam Vet; 2017:252-253. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.870 (2026-08-01, PENDING REVIEW). Prednisone is used in rabbits for Adjunct therapy for thymoma / mediastinal neoplasia; antiinflammatory. Routes documented in rabbits: PO. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Prednisone in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Deltasone
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 0.5–2 mg/kg | q12-24h | Adjunct therapy for thymoma / mediastinal neoplasia; antiinflammatory | Weak | Andres K, Kent M, Seidlecki C, et al. The use of megavoltage radiation therapy in the treatment of thymoma in rabbits: 19 cases. Vet Comp Oncol. 2012;10:82-94. | Donnelly TM. Rabbit with cutaneous lymphoma: chemotherapy options and drug doses. VIN Vet-to-Vet Message Boards. www.vin.com. | Heatley JJ, Smith AN. Spontaneous neoplasms of lagomorphs. Vet Clin North Am Exot Anim Pract. 2004;7:561-577. | Perez K, Chen S, Antinoff N. Use of prednisolone in six rabbits (Oryctolagus cuniculus) with cranial mediastinal disease. Proc Conf Annu Assoc Exot Mam Vet; 2017:252-253. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.870 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your rabbit's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Prodrug converted to prednisolone by the liver. Modulates gene transcription via glucocorticoid receptors, suppressing inflammatory/immune responses.
INEFFECTIVE in cats (cannot convert to prednisolone — use prednisolone instead). PU/PD, polyphagia. GI ulceration. Iatrogenic Cushing's with chronic use. Taper when discontinuing.
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Prednisone dose range in rabbits, with cited source references: PO 0.5–2 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Prednisone in rabbits: PO.
Prednisone is indicated in rabbits for: Adjunct therapy for thymoma / mediastinal neoplasia; antiinflammatory.
These are general warnings for Prednisone across species; consult the rabbit dosing table above for species-specific guidance. INEFFECTIVE in cats (cannot convert to prednisolone — use prednisolone instead). PU/PD, polyphagia. GI ulceration. Iatrogenic Cushing's with chronic use. Taper when discontinuing.
Why a species-specific page? Prednisone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.