Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Buprenorphine is used in rabbit for Post-operative analgesia, Acute pain management, Pain management, post-operative. Routes documented in rabbit: IM, IV, SC. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 3 cited dose rules for Buprenorphine in rabbit, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Simbadol, Buprenex
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 0.01–0.05 mg/kg | q6-12h | 24-72 hours post-operatively | Post-operative analgesia | Moderate | Carpenter's Exotic Animal Formulary, 6th Ed |
| IV | 0.01–0.05 mg/kg | q6-12h | As needed | Acute pain management | Moderate | Carpenter's Exotic Animal Formulary, 6th Ed |
| SC | 0.01–0.05 mg/kg | q6-12h | As needed | Pain management, post-operative | Moderate | Carpenter's Exotic Animal Formulary, 6th Ed |
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These ranges are per kg. Enter your rabbit's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Partial agonist at mu-opioid receptors with high receptor affinity. Provides analgesia with a ceiling effect on respiratory depression.
OTM (oral transmucosal) absorption effective in cats. Ceiling effect limits maximum analgesia. Difficult to reverse with naloxone due to high receptor affinity.
Species-specific contraindications and adverse-reaction reports for rabbit may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Buprenorphine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbit — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.