Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Phenobarbital is dosed at 1–2 mg/kg PO q12h in rabbits, per Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery, Appendix Formulary, Table A.5 (Miscellaneous Agents Used in Small Mammals), p.642, Rabbits column — LOCATOR CONVENTION 2026-08-07: the bare 'p.642' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.630; verified by finding the drug named there. If you are holding the book, turn to p.630. — SOURCE EDITION: Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery — ISBN 9780323484350, https://openlibrary.org/isbn/9780323484350. Phenobarbital is used in rabbits for Seizures. Routes documented in rabbits: PO. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Phenobarbital in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Luminal, Solfoton
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1–2 mg/kg | q12h | Long-term | Seizures |
| Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery, Appendix Formulary, Table A.5 (Miscellaneous Agents Used in Small Mammals), p.642, Rabbits column — LOCATOR CONVENTION 2026-08-07: the bare 'p.642' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.630; verified by finding the drug named there. If you are holding the book, turn to p.630. — SOURCE EDITION: Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery — ISBN 9780323484350, https://openlibrary.org/isbn/9780323484350 |
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These ranges are per kg. Enter your rabbit's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Enhances GABA-A receptor activity by prolonging chloride channel opening. Also blocks AMPA/glutamate receptors. Raises seizure threshold.
First-line anticonvulsant for dogs. Hepatotoxicity with chronic use (monitor liver enzymes and serum levels). PU/PD, polyphagia, sedation (often transient). Hepatic enzyme inducer (many drug interactions). DEA controlled.
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Phenobarbital dose range in rabbits, with cited source references: PO 1–2 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Phenobarbital in rabbits: PO.
Cited course lengths for Phenobarbital in rabbits include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Phenobarbital is indicated in rabbits for: Seizures.
These are general warnings for Phenobarbital across species; consult the rabbit dosing table above for species-specific guidance. First-line anticonvulsant for dogs. Hepatotoxicity with chronic use (monitor liver enzymes and serum levels). PU/PD, polyphagia, sedation (often transient). Hepatic enzyme inducer (many drug interactions). DEA controlled.
Why a species-specific page? Phenobarbital pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.