Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Phenobarbital is used in dog for Status epilepticus (loading), Epilepsy (maintenance). Routes documented in dog: IV, PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Phenobarbital in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Luminal, Solfoton
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Enhances GABA-A receptor activity by prolonging chloride channel opening. Also blocks AMPA/glutamate receptors. Raises seizure threshold.
First-line anticonvulsant for dogs. Hepatotoxicity with chronic use (monitor liver enzymes and serum levels). PU/PD, polyphagia, sedation (often transient). Hepatic enzyme inducer (many drug interactions). DEA controlled.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Phenobarbital pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.