Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Potassium Bromide is dosed at 20–40 mg/kg PO q24h in dogs, per Boothe DM, Dewey C, Carpenter DM. Comparison of phenobarbital with bromide as a first-choice antiepileptic drug for treatment of epilepsy in dogs. J Am Vet Med Assoc. 2012;240(9):1073-1083. doi:10.2460/javma.240.9.1073; Podell M, Volk HA, Berendt M, et al. 2015 ACVIM small animal consensus statement on seizure management in dogs. J Vet Intern Med. 2016;30(2):477-490. (Plumb's Bromides, references on the maintenance-dosage line) doi:10.1111/jvim.13841 — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.348 (2026-08-01).. Potassium Bromide is used in dogs for Epilepsy (adjunctive or monotherapy). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Potassium Bromide in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: K-BroVet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 20–40 mg/kg | q24h | Long-term (lifelong) | Epilepsy (adjunctive or monotherapy) | Strong | Boothe DM, Dewey C, Carpenter DM. Comparison of phenobarbital with bromide as a first-choice antiepileptic drug for treatment of epilepsy in dogs. J Am Vet Med Assoc. 2012;240(9):1073-1083. doi:10.2460/javma.240.9.1073; Podell M, Volk HA, Berendt M, et al. 2015 ACVIM small animal consensus statement on seizure management in dogs. J Vet Intern Med. 2016;30(2):477-490. (Plumb's Bromides, references on the maintenance-dosage line) doi:10.1111/jvim.13841 — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.348 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Bromide competes with chloride at GABA-A receptor chloride channels, hyperpolarizing neurons and raising seizure threshold. Also competes with chloride in renal tubules.
Long half-life (24 days in dogs) — takes 3-4 months for steady state. Loading dose can shorten this. CONTRAINDICATED in cats (severe respiratory disease/pneumonitis). Monitor serum bromide levels. Dietary chloride changes affect levels. Pancreatitis risk.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Potassium Bromide dose range in dogs, with cited source references: PO 20–40 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Potassium Bromide in dogs: PO.
Cited course lengths for Potassium Bromide in dogs include: Long-term (lifelong). Duration depends on the indication — match it to the specific dose rule in the table above.
Potassium Bromide is indicated in dogs for: Epilepsy (adjunctive or monotherapy).
These are general warnings for Potassium Bromide across species; consult the dog dosing table above for species-specific guidance. Long half-life (24 days in dogs) — takes 3-4 months for steady state. Loading dose can shorten this. CONTRAINDICATED in cats (severe respiratory disease/pneumonitis). Monitor serum bromide levels. Dietary chloride changes affect levels. Pancreatitis risk.
Why a species-specific page? Potassium Bromide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.