Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Potassium Bromide is dosed at 20–40 mg/kg PO q24h in dogs, per Boothe DM, Dewey C, Carpenter DM. Comparison of phenobarbital with bromide as a first-choice antiepileptic drug for treatment of epilepsy in dogs. J Am Vet Med Assoc. 2012;240(9):1073-1083. doi:10.2460/javma.240.9.1073; Podell M, Volk HA, Berendt M, et al. 2015 ACVIM small animal consensus statement on seizure management in dogs. J Vet Intern Med. 2016;30(2):477-490. (Plumb's Bromides, references on the maintenance-dosage line) doi:10.1111/jvim.13841 — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.348 (2026-08-01). — Plumb's 10th ed (held) printed p.137-139 (corpus PDF p.164-166), Bromides monograph, Dosages — DOGS [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Citrate, Potassium monograph, a urinary alkalinizer]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705; Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Potassium Bromide is used in dogs for Epilepsy (adjunctive or monotherapy). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Potassium Bromide in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: K-BroVet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 20–40 mg/kg | q24h | Long-term (lifelong) | Epilepsy (adjunctive or monotherapy) | Strong | Boothe DM, Dewey C, Carpenter DM. Comparison of phenobarbital with bromide as a first-choice antiepileptic drug for treatment of epilepsy in dogs. J Am Vet Med Assoc. 2012;240(9):1073-1083. doi:10.2460/javma.240.9.1073; Podell M, Volk HA, Berendt M, et al. 2015 ACVIM small animal consensus statement on seizure management in dogs. J Vet Intern Med. 2016;30(2):477-490. (Plumb's Bromides, references on the maintenance-dosage line) doi:10.1111/jvim.13841 — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.348 (2026-08-01). — Plumb's 10th ed (held) printed p.137-139 (corpus PDF p.164-166), Bromides monograph, Dosages — DOGS [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Citrate, Potassium monograph, a urinary alkalinizer]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705; Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Carpenter's Exotic Animal Formulary — ISBN 9780323833929, |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 20–40 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.348 | after which the dose is decreased to the maintenance dose (20-40 mg/kg p.o. q24h). If seizures resolve sooner, it is advisable to decrease the loading dos |
| 600–1000 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.348 | r to reduce adverse effects. A single loading dose of 600-1000 mg/kg p.o. can be given but this is likely to result in excessive sedation, ataxia and p |
| 100 | — | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.349 | oading schedule for liquid bromide (250 mg/ml) by rectum is 100 mg/kg q4h for 6 doses (total 600 mg/kg) |
| 600 | — |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Bromide competes with chloride at GABA-A receptor chloride channels, hyperpolarizing neurons and raising seizure threshold. Also competes with chloride in renal tubules.
Long half-life (24 days in dogs) — takes 3-4 months for steady state. Loading dose can shorten this. CONTRAINDICATED in cats (severe respiratory disease/pneumonitis). Monitor serum bromide levels. Dietary chloride changes affect levels. Pancreatitis risk.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Potassium Bromide dose range in dogs, with cited source references: PO 20–40 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Potassium Bromide in dogs: PO.
Cited course lengths for Potassium Bromide in dogs include: Long-term (lifelong). Duration depends on the indication — match it to the specific dose rule in the table above.
Potassium Bromide is indicated in dogs for: Epilepsy (adjunctive or monotherapy).
These are general warnings for Potassium Bromide across species; consult the dog dosing table above for species-specific guidance. Long half-life (24 days in dogs) — takes 3-4 months for steady state. Loading dose can shorten this. CONTRAINDICATED in cats (severe respiratory disease/pneumonitis). Monitor serum bromide levels. Dietary chloride changes affect levels. Pancreatitis risk.
Why a species-specific page? Potassium Bromide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| e (250 mg/ml) by rectum is 100 mg/kg q4h for 6 doses (total 600 mg/kg) |
| Dose (mg/ml) | Route | Source | As printed |
|---|---|---|---|
| 250 | — | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.349 | a 24-hour period. The loading schedule for liquid bromide (250 mg/ml) by rectum is 100 mg/kg q4h for 6 doses (total 600 mg/kg) |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.