Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Amikacin is dosed at 15–30 mg/kg IV q24h in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.76 (2026-08-01).. Amikacin is used in dogs for Severe gram-negative infections. Routes documented in dogs: IV, SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Amikacin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Amiglyde-V, Amikin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 15–30 mg/kg | q24h | 7-14 days | Severe gram-negative infections | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.76 (2026-08-01). |
| SC | 15–30 mg/kg | q24h | 7-14 days | Severe gram-negative infections |
| Strong |
| Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.76 (2026-08-01). |
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Irreversibly binds 30S ribosomal subunit, inhibiting bacterial protein synthesis. Concentration-dependent bactericidal activity.
Nephrotoxic and ototoxic. Monitor renal function (BUN, creatinine). Ensure adequate hydration. Avoid concurrent use with other nephrotoxic drugs. Neuromuscular blockade risk.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Amikacin dose ranges in dogs, with cited source references: IV 15–30 mg/kg q24h; SC 15–30 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Amikacin in dogs: IV, SC.
Cited course lengths for Amikacin in dogs include: 7-14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Amikacin is indicated in dogs for: Severe gram-negative infections.
These are general warnings for Amikacin across species; consult the dog dosing table above for species-specific guidance. Nephrotoxic and ototoxic. Monitor renal function (BUN, creatinine). Ensure adequate hydration. Avoid concurrent use with other nephrotoxic drugs. Neuromuscular blockade risk.
Why a species-specific page? Amikacin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.