Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Amikacin is dosed at 15–30 mg/kg IV, IM, SC q24h in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (held), Amikacin Systemic monograph, printed p.49 (corpus PDF p.76), DOGS - "Susceptible infections and empirical therapy (extra-label): 15 - 30 mg/kg IV, IM, SC once daily." [CORRECTED - the page previously named, printed p.1341, is Amikacin Ophthalmic and carries no systemic dose.] ISBN 9781394172207. Amikacin is used in dogs for Severe gram-negative infections. Routes documented in dogs: IV, IM, SC, SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Amikacin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Amiglyde-V, Amikin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV, IM, SC | 15–30 mg/kg | q24h | 7-14 days | Severe gram-negative infections | Strong | Plumb's Veterinary Drug Handbook, 10th ed (held), Amikacin Systemic monograph, printed p.49 (corpus PDF p.76), DOGS - "Susceptible infections and empirical therapy (extra-label): 15 - 30 mg/kg IV, IM, SC once daily." [CORRECTED - the page previously named, printed p.1341, is Amikacin Ophthalmic and carries no systemic dose.] ISBN 9781394172207 |
| SC | 15–30 mg/kg | q24h | 7-14 days | Severe gram-negative infections | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.76 (2026-08-01). — Plumb's 10th ed (held) printed p.1341, Amikacin Ophthalmic monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 15–30 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.32 | 15-30 mg/kg i.v, i.m., s.c. q24h. Due to a lower volume of distribution in Greyhounds a lower dose of |
| 12 | — | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.32 | lower volume of distribution in Greyhounds a lower dose of 12 mg/kg is recommended in this breed and other sight hounds |
| 15–30 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.54 | • 15-30 mg/kg q24h IV, IM, or SQ. • 10-14 mg/kg q24h IV, IM, or SQ. |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Irreversibly binds 30S ribosomal subunit, inhibiting bacterial protein synthesis. Concentration-dependent bactericidal activity.
Nephrotoxic and ototoxic. Monitor renal function (BUN, creatinine). Ensure adequate hydration. Avoid concurrent use with other nephrotoxic drugs. Neuromuscular blockade risk.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Amikacin dose ranges in dogs, with cited source references: IV, IM, SC 15–30 mg/kg q24h; SC 15–30 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Amikacin in dogs: IV, IM, SC, SC.
Cited course lengths for Amikacin in dogs include: 7-14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Amikacin is indicated in dogs for: Severe gram-negative infections.
These are general warnings for Amikacin across species; consult the dog dosing table above for species-specific guidance. Nephrotoxic and ototoxic. Monitor renal function (BUN, creatinine). Ensure adequate hydration. Avoid concurrent use with other nephrotoxic drugs. Neuromuscular blockade risk.
Why a species-specific page? Amikacin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 10–14 |
| IV |
| Papich Saunders Handbook of Veterinary Drugs, 4th edp.54 |
| • 15-30 mg/kg q24h IV, IM, or SQ. • 10-14 mg/kg q24h IV, IM, or SQ. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.