Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Amikacin is dosed at 250–500 mg per joint INTRA-ARTICULAR q24-48h in horses, per Plumb's Veterinary Drug Handbook, 10th ed, Amikacin Systemic monograph, printed p.50, HORSES - treatment of septic joints, intra-articular. ISBN 9781394172207. Amikacin is used in horses for Septic arthritis (local), Gram-negative sepsis. Routes documented in horses: INTRA-ARTICULAR, IV. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 2 cited dose rules for Amikacin in horses, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Amiglyde-V, Amikin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| INTRA-ARTICULAR | 250–500 mg per joint | q24-48h | — | Septic arthritis (local) | Moderate | Plumb's Veterinary Drug Handbook, 10th ed, Amikacin Systemic monograph, printed p.50, HORSES - treatment of septic joints, intra-articular. ISBN 9781394172207Compilation only — we have not located an independent source that prints this figure. |
| IV | 10 mg/kg | q24h (once daily) | 5-7 days | Gram-negative sepsis | Weak | Plumb's Veterinary Drug Handbook, 10th ed (2023), p.76-77 — Amikacin, Systemic, Dosages, HORSES (adults) — Plumb's 10th ed printed p.1341, Amikacin Ophthalmic monograph.Compilation only — we have not located an independent source that prints this figure. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 4.4–6.6 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.54 | • Adult: 4.4-6.6 mg/kg q12h IM or IV or 10 mg/kg q24h IV or IM. |
| 10 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.54 | • Adult: 4.4-6.6 mg/kg q12h IM or IV or 10 mg/kg q24h IV or IM. |
| 20–25 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.54 | • Foal: 20-25 mg/kg q24h IV or IM or 6.6 mg/kg q8h IV or IM. |
| 6.6 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.54 | • Foal: 20-25 mg/kg q24h IV or IM or 6.6 mg/kg q8h IV or IM. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Irreversibly binds 30S ribosomal subunit, inhibiting bacterial protein synthesis. Concentration-dependent bactericidal activity.
Nephrotoxic and ototoxic. Monitor renal function (BUN, creatinine). Ensure adequate hydration. Avoid concurrent use with other nephrotoxic drugs. Neuromuscular blockade risk.
Species-specific contraindications and adverse-reaction reports for horses may differ from canine / feline reference data — consult the primary citations listed with each rule.
Amikacin dose ranges in horses, with cited source references: INTRA-ARTICULAR 250–500 mg per joint q24-48h; IV 10 mg/kg q24h (once daily). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Amikacin in horses: INTRA-ARTICULAR, IV.
Cited course lengths for Amikacin in horses include: 5-7 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Amikacin is indicated in horses for: Septic arthritis (local), Gram-negative sepsis.
These are general warnings for Amikacin across species; consult the horse dosing table above for species-specific guidance. Nephrotoxic and ototoxic. Monitor renal function (BUN, creatinine). Ensure adequate hydration. Avoid concurrent use with other nephrotoxic drugs. Neuromuscular blockade risk.
Why a species-specific page? Amikacin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horses — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.