Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Chloramphenicol is dosed at 50 mg/kg PO q6h in horses, per Brumbaugh G. Clinical pharmacology and the pediatric patient. Presented at: 45th Annual AAEP Convention; 1999. doi:10.1007/s004670050514; USPC. Veterinary Information- Appendix III. In: Drug Information for the Health Professional. Vol 2. United States Pharmacopeial Convention; 1990:2811-2860. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.275 (2026-08-01). — Plumb's 10th ed (held) printed p.245, Chloramphenicol monograph spanning p.245-248; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Chloramphenicol is used in horses for Susceptible bacterial infections. Routes documented in horses: PO. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 1 cited dose rule for Chloramphenicol in horses, drawn from published veterinary references. Verify against current literature before clinical use.
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 50 mg/kg | q6h | 5-7 days | Susceptible bacterial infections | Moderate | Brumbaugh G. Clinical pharmacology and the pediatric patient. Presented at: 45th Annual AAEP Convention; 1999. doi:10.1007/s004670050514; USPC. Veterinary Information- Appendix III. In: Drug Information for the Health Professional. Vol 2. United States Pharmacopeial Convention; 1990:2811-2860. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.275 (2026-08-01). — Plumb's 10th ed (held) printed p.245, Chloramphenicol monograph spanning p.245-248; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 35–50 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.178 | • 35-50 mg/kg q6-8h PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Binds to 50S ribosomal subunit, inhibiting peptidyl transferase and bacterial protein synthesis. Bacteriostatic.
Human health hazard: wear gloves when handling (aplastic anemia risk in humans). May cause bone marrow suppression in cats. Monitor CBC during prolonged use.
Species-specific contraindications and adverse-reaction reports for horses may differ from canine / feline reference data — consult the primary citations listed with each rule.
Chloramphenicol dose range in horses, with cited source references: PO 50 mg/kg q6h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Chloramphenicol in horses: PO.
Cited course lengths for Chloramphenicol in horses include: 5-7 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Chloramphenicol is indicated in horses for: Susceptible bacterial infections.
These are general warnings for Chloramphenicol across species; consult the horse dosing table above for species-specific guidance. Human health hazard: wear gloves when handling (aplastic anemia risk in humans). May cause bone marrow suppression in cats. Monitor CBC during prolonged use.
Why a species-specific page? Chloramphenicol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horses — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.