Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Enrofloxacin is dosed at 5–7.5 mg/kg IV q24h in horses, per Haggett EF, Wilson WD. Overview of the use of antimicrobials for the treatment of bacterial infections in horses. Equine Vet Educ. 2008;20(8):433-448. doi:10.2746/095777308x338893 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.480 (2026-08-01).. Enrofloxacin is used in horses for Bacterial infection, Susceptible bacterial infections. Routes documented in horses: IV. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 2 cited dose rules for Enrofloxacin in horses, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Baytril
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 5–7.5 mg/kg | q24h | 5-10 days | Bacterial infection | Moderate | Haggett EF, Wilson WD. Overview of the use of antimicrobials for the treatment of bacterial infections in horses. Equine Vet Educ. 2008;20(8):433-448. doi:10.2746/095777308x338893 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.480 (2026-08-01). |
| IV | 5–7.5 mg/kg | q24h | 5-10 days | Susceptible bacterial infections | Moderate | Haggett EF, Wilson WD. Overview of the use of antimicrobials for the treatment of bacterial infections in horses. Equine Vet Educ. 2008;20(8):433-448. doi:10.2746/095777308x338893 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.480 (2026-08-01). |
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These ranges are per kg. Enter your horse's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription.
Avoid in growing animals (cartilage damage). Do NOT use in cats at doses >5mg/kg (retinal toxicity). Avoid concurrent use with theophylline.
Species-specific contraindications and adverse-reaction reports for horses may differ from canine / feline reference data — consult the primary citations listed with each rule.
Enrofloxacin dose ranges in horses, with cited source references: IV 5–7.5 mg/kg q24h; IV 5–7.5 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Enrofloxacin in horses: IV.
Cited course lengths for Enrofloxacin in horses include: 5-10 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Enrofloxacin is indicated in horses for: Bacterial infection, Susceptible bacterial infections.
These are general warnings for Enrofloxacin across species; consult the horse dosing table above for species-specific guidance. Avoid in growing animals (cartilage damage). Do NOT use in cats at doses >5mg/kg (retinal toxicity). Avoid concurrent use with theophylline.
Why a species-specific page? Enrofloxacin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horses — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.