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Gentamicin for Horse

Equine · Equus caballus · typical adult weight 350.00–700.00 kg

Gentamicin is used in horse for Gram-negative sepsis, Gram-negative septicemia. Routes documented in horse: IV. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 2 cited dose rules for Gentamicin in horse, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Gentocin

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
IV6.6 mg/kgq24h5-7 daysGram-negative sepsisStrongPlumb's Veterinary Drug Handbook, 9th Ed
IV6.6 mg/kgq24h5-10 daysGram-negative septicemiaStrongPlumb's Veterinary Drug Handbook

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These ranges are per kg. Enter your horse's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Irreversibly binds 30S ribosomal subunit, inhibiting bacterial protein synthesis. Concentration-dependent killing with post-antibiotic effect.

Side effects & warnings

Highly nephrotoxic. Monitor renal values. Maintain hydration. Ototoxic. Avoid in dehydrated patients. Neuromuscular blockade risk. Extended-interval dosing preferred.

Species-specific contraindications and adverse-reaction reports for horse may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Antibiotic drugs with horse dosing

Gentamicin dosing in other species

Why a species-specific page? Gentamicin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horse — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.