Cat · Felis catus · typical adult weight 2.50–7.00 kg
Chloramphenicol is used in cat for Severe systemic infections requiring CNS penetration, Susceptible infections, Bacterial conjunctivitis (ophthalmic). Routes documented in cat: IV, PO, TOPICAL. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 3 cited dose rules for Chloramphenicol in cat, drawn from published veterinary references. Verify against current literature before clinical use.
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 12.5–25 mg/kg | q12h | Until oral feasible | Severe systemic infections requiring CNS penetration | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 12.5–25 mg/kg | q12h | 7-14 days | Susceptible infections | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| TOPICAL | 0 topical | q6-8h | 7-14 days | Bacterial conjunctivitis (ophthalmic) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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Binds to 50S ribosomal subunit, inhibiting peptidyl transferase and bacterial protein synthesis. Bacteriostatic.
Human health hazard: wear gloves when handling (aplastic anemia risk in humans). May cause bone marrow suppression in cats. Monitor CBC during prolonged use.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Chloramphenicol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.