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Aztreonam for Dog

Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg

Aztreonam is used in dog for Severe gram-negative infections. Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Aztreonam in dog, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Azactam

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
IV30–50 mg/kgq8h7-14 daysSevere gram-negative infectionsWeakPlumb's Veterinary Drug Handbook, 9th Ed

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Mechanism of action

Binds penicillin-binding protein 3 (PBP-3) of gram-negative bacteria, inhibiting cell wall synthesis. Active only against aerobic gram-negative organisms.

Side effects & warnings

No cross-reactivity with penicillin allergy in most cases. Limited veterinary data. Monitor renal function with prolonged use.

Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Antibiotic drugs with dog dosing

Aztreonam dosing in other species

Why a species-specific page? Aztreonam pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.