Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Aztreonam is dosed at 30–50 mg/kg IV q8h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Aztreonam is used in dogs for Severe gram-negative infections. Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Aztreonam in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Azactam
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 30–50 mg/kg | q8h | 7-14 days | Severe gram-negative infections | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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Binds penicillin-binding protein 3 (PBP-3) of gram-negative bacteria, inhibiting cell wall synthesis. Active only against aerobic gram-negative organisms.
No cross-reactivity with penicillin allergy in most cases. Limited veterinary data. Monitor renal function with prolonged use.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Aztreonam dose range in dogs, with cited source references: IV 30–50 mg/kg q8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Aztreonam in dogs: IV.
Cited course lengths for Aztreonam in dogs include: 7-14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Aztreonam is indicated in dogs for: Severe gram-negative infections.
These are general warnings for Aztreonam across species; consult the dog dosing table above for species-specific guidance. No cross-reactivity with penicillin allergy in most cases. Limited veterinary data. Monitor renal function with prolonged use.
Why a species-specific page? Aztreonam pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.