Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Nitazoxanide is dosed at 75–150 mg/kg PO once in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.933, Nitazoxanide monograph spanning p.933-934; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.934, Nitazoxanide monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 — CORRECTED 2026-08-10: Plumb's 10th ed printed p.934 (corpus plumb p.961) DOGS: "Giardia spp associated diarrhea (extra-label): 75 - 150 mg/kg PO once".. Nitazoxanide is used in dogs for Cryptosporidiosis, Giardia. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Nitazoxanide in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Alinia, Navigator
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 75–150 mg/kg | once | Single dose | Cryptosporidiosis, Giardia | Weak | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.933, Nitazoxanide monograph spanning p.933-934; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.934, Nitazoxanide monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 — CORRECTED 2026-08-10: Plumb's 10th ed printed p.934 (corpus plumb p.961) DOGS: "Giardia spp associated diarrhea (extra-label): 75 - 150 mg/kg PO once". |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction essential for anaerobic energy metabolism.
Active against Cryptosporidium, Giardia, and some helminths. GI upset common. Limited veterinary efficacy data. Give with food.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Nitazoxanide dose range in dogs, with cited source references: PO 75–150 mg/kg once. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Nitazoxanide in dogs: PO.
Cited course lengths for Nitazoxanide in dogs include: Single dose. Duration depends on the indication — match it to the specific dose rule in the table above.
Nitazoxanide is indicated in dogs for: Cryptosporidiosis, Giardia.
These are general warnings for Nitazoxanide across species; consult the dog dosing table above for species-specific guidance. Active against Cryptosporidium, Giardia, and some helminths. GI upset common. Limited veterinary efficacy data. Give with food.
Why a species-specific page? Nitazoxanide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.