Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Mupirocin is used in dogs for MRSA/MRSP superficial skin infections, Superficial pyoderma, MRSP. Routes documented in dogs: Topical. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Mupirocin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Bactroban, Muricin Vet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Topical | CAVEAT FROM SOURCE: Move the citation off Plumb's — Plumb's 9th ed (printed p.1432) prints only "labeled for twice daily application on dogs" (q12h), so it supports the q12h end but NOT the q8h end | q8-12h | 5-14 days | MRSA/MRSP superficial skin infections | Weak | BSAVA Small Animal Formulary, 10th ed., Part A — Canine and Feline, "Mupirocin (Pseudomonic acid A) (Bactroban*) POM", DOSES, printed p.277 (corpus PDF p.293) — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705 |
| Topical | Avoid large wounds (PEG base) | q12h | 7-14 days | Superficial pyoderma, MRSP | Strong | MURICIN - Mupirocin Ointment [US Product Label for Dogs]. Dechra Veterinary Products; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ded00eb4-5edb-46d6-9f86-460d9de01d0b — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1459 (2026-08-01). — Plumb's 10th ed (held) printed p.1432, Mupirocin, Topical monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
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Inhibits bacterial isoleucyl-tRNA synthetase, blocking protein synthesis. Bactericidal at concentrations achieved topically.
Excellent anti-staphylococcal activity including some MRSP. Polyethylene glycol base — avoid on large open wounds (PEG absorption and nephrotoxicity). Do not use with other topicals.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Mupirocin dose ranges in dogs, with cited source references: Topical CAVEAT FROM SOURCE: Move the citation off Plumb's — Plumb's 9th ed (printed p.1432) prints only "labeled for twice daily application on dogs" (q12h), so it supports the q12h end but NOT the q8h end q8-12h; Topical Avoid large wounds (PEG base) q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Mupirocin in dogs: Topical.
Cited course lengths for Mupirocin in dogs include: 5-14 days; 7-14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Mupirocin is indicated in dogs for: MRSA/MRSP superficial skin infections, Superficial pyoderma, MRSP.
These are general warnings for Mupirocin across species; consult the dog dosing table above for species-specific guidance. Excellent anti-staphylococcal activity including some MRSP. Polyethylene glycol base — avoid on large open wounds (PEG absorption and nephrotoxicity). Do not use with other topicals.
Why a species-specific page? Mupirocin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.