Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Cyclosporine is used in dog for Atopic dermatitis, Keratoconjunctivitis sicca (KCS). Routes documented in dog: PO, TOPICAL. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Cyclosporine in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Atopica, Optimmune
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds cyclophilin, inhibiting calcineurin phosphatase. Blocks IL-2 transcription in T-helper lymphocytes, suppressing cell-mediated immunity.
GI upset common initially (improves with time). Give on empty stomach or freeze capsules. Gingival hyperplasia. Immunosuppression — monitor for infections. Do not use modified and non-modified forms interchangeably.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Cyclosporine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.