Bird · Cacatua alba · typical adult weight 0.40–0.70 kg
Cyclosporine is dosed at 5–10 mg/kg PO q12h; reduce to q24h after 3 months in umbrella cockatoos, per Kleinschmidt LM, Hoppes SM, Musser JMB, Tizard I, Heatley JJ. Use of Cyclosporine and Itraconazole as Palliative Treatment for Proventricular Dilatation Disease in Psittacine Birds. Vet Sci. 2025;12(5):459. doi:10.3390/vetsci12050459 https://europepmc.org/article/PMC/PMC12115444. Cyclosporine is used in umbrella cockatoos for Proventricular dilatation disease / parrot bornavirus (palliative immunosuppression). Routes documented in umbrella cockatoos: PO. A typical adult umbrella cockatoo weighs 0.40–0.70 kg. ExoticRx lists 1 cited dose rule for Cyclosporine in umbrella cockatoos, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Atopica, Optimmune
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 5–10 mg/kg | q12h; reduce to q24h after 3 months | Proventricular dilatation disease / parrot bornavirus (palliative immunosuppression) | Weak | Kleinschmidt LM, Hoppes SM, Musser JMB, Tizard I, Heatley JJ. Use of Cyclosporine and Itraconazole as Palliative Treatment for Proventricular Dilatation Disease in Psittacine Birds. Vet Sci. 2025;12(5):459. doi:10.3390/vetsci12050459 https://europepmc.org/article/PMC/PMC12115444 |
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Binds cyclophilin, inhibiting calcineurin phosphatase. Blocks IL-2 transcription in T-helper lymphocytes, suppressing cell-mediated immunity.
GI upset common initially (improves with time). Give on empty stomach or freeze capsules. Gingival hyperplasia. Immunosuppression — monitor for infections. Do not use modified and non-modified forms interchangeably.
Species-specific contraindications and adverse-reaction reports for umbrella cockatoos may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cyclosporine dose range in umbrella cockatoos, with cited source references: PO 5–10 mg/kg q12h; reduce to q24h after 3 months. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cyclosporine in umbrella cockatoos: PO.
Cyclosporine is indicated in umbrella cockatoos for: Proventricular dilatation disease / parrot bornavirus (palliative immunosuppression).
These are general warnings for Cyclosporine across species; consult the umbrella cockatoo dosing table above for species-specific guidance. GI upset common initially (improves with time). Give on empty stomach or freeze capsules. Gingival hyperplasia. Immunosuppression — monitor for infections. Do not use modified and non-modified forms interchangeably.
Why a species-specific page? Cyclosporine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in umbrella cockatoos — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.