Cat · Felis catus · typical adult weight 2.50–7.00 kg
Cyclosporine is dosed at 7 mg/kg PO q24h in cats, per ATOPICA FOR CATS- Cyclosporine Solution [US Product Label]. Elanco; 2015. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=47f70173-a1d9-4156-9a7f-0f296e5dd64b — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.352 (2026-08-01). — Plumb's 10th ed (held) printed p.322, Cyclosporine (Systemic) monograph spanning p.322-326; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Cyclosporine is used in cats for Allergic dermatitis, eosinophilic granuloma complex. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Cyclosporine in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Atopica, Optimmune
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 7 mg/kg | q24h | Long-term | Allergic dermatitis, eosinophilic granuloma complex | Moderate | ATOPICA FOR CATS- Cyclosporine Solution [US Product Label]. Elanco; 2015. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=47f70173-a1d9-4156-9a7f-0f296e5dd64b — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.352 (2026-08-01). — Plumb's 10th ed (held) printed p.322, Cyclosporine (Systemic) monograph spanning p.322-326; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 7.5 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.224 | • 7.5 mg/kg per day, PO. Some cats can be controlled with administration of this |
| 3–5 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.224 | higher (e.g., 3-5 mg/kg q12h PO). |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Binds cyclophilin, inhibiting calcineurin phosphatase. Blocks IL-2 transcription in T-helper lymphocytes, suppressing cell-mediated immunity.
GI upset common initially (improves with time). Give on empty stomach or freeze capsules. Gingival hyperplasia. Immunosuppression — monitor for infections. Do not use modified and non-modified forms interchangeably.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cyclosporine dose range in cats, with cited source references: PO 7 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cyclosporine in cats: PO.
Cited course lengths for Cyclosporine in cats include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Cyclosporine is indicated in cats for: Allergic dermatitis, eosinophilic granuloma complex.
These are general warnings for Cyclosporine across species; consult the cat dosing table above for species-specific guidance. GI upset common initially (improves with time). Give on empty stomach or freeze capsules. Gingival hyperplasia. Immunosuppression — monitor for infections. Do not use modified and non-modified forms interchangeably.
Why a species-specific page? Cyclosporine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.