Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Apoquel is dosed at 0.4–0.6 mg/kg PO q12h x 14 days, then q24h in dogs, per APOQUEL - Oclacitinib Maleate Tablet, Coated [US Product Label for Dogs]. Kalamazoo, MI: Zoetis Inc.; 2020. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a39a0298-6453-4c21-a3b0-01c1a52a109b — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.976 (2026-08-01).. Apoquel is used in dogs for Atopic dermatitis, allergic pruritus. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Apoquel in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Oclacitinib Maleate Tablet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.4–0.6 mg/kg | q12h x 14 days, then q24h | Long-term | Atopic dermatitis, allergic pruritus | Strong | APOQUEL - Oclacitinib Maleate Tablet, Coated [US Product Label for Dogs]. Kalamazoo, MI: Zoetis Inc.; 2020. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a39a0298-6453-4c21-a3b0-01c1a52a109b — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.976 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Preferential JAK1 inhibitor blocking IL-31 and other pruritogenic cytokine signaling. Rapid onset antipruritic effect (4 hours).
Same as oclacitinib. Veterinary-specific product. Twice daily for 14 days then once daily. Not for dogs <12 months. Monitor for neoplasia. Do not use with other immunosuppressants.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Apoquel dose range in dogs, with cited source references: PO 0.4–0.6 mg/kg q12h x 14 days, then q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Apoquel in dogs: PO.
Cited course lengths for Apoquel in dogs include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Apoquel is indicated in dogs for: Atopic dermatitis, allergic pruritus.
These are general warnings for Apoquel across species; consult the dog dosing table above for species-specific guidance. Same as oclacitinib. Veterinary-specific product. Twice daily for 14 days then once daily. Not for dogs <12 months. Monitor for neoplasia. Do not use with other immunosuppressants.
Why a species-specific page? Apoquel pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.