ExoticRx · exoticrx.com/drugs/apoquel
US brand names:Oclacitinib Maleate Tablet
Apoquel is dosed at 0.4–0.6 mg/kg PO q12h x 14 days, then q24h in dogs, per APOQUEL - Oclacitinib Maleate Tablet, Coated [US Product Label for Dogs]. Kalamazoo, MI: Zoetis Inc.; 2020. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a39a0298-6453-4c21-a3b0-01c1a52a109b — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.976 (2026-08-01).. Verify against current literature before clinical use.
Preferential JAK1 inhibitor blocking IL-31 and other pruritogenic cytokine signaling. Rapid onset antipruritic effect (4 hours).
Same as oclacitinib. Veterinary-specific product. Twice daily for 14 days then once daily. Not for dogs <12 months. Monitor for neoplasia. Do not use with other immunosuppressants.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.4–0.6 mg/kg | q12h x 14 days, then q24h | Strong | APOQUEL - Oclacitinib Maleate Tablet, Coated [US Product Label for Dogs]. Kalamazoo, MI: Zoetis Inc.; 2020. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a39a0298-6453-4c21-a3b0-01c1a52a109b — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.976 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.