Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Lufenuron is dosed at 10 mg/kg PO q30d in dogs, per PROGRAM FLAVOR TABS - lufenuron tablet [US canine and feline product label]. In: Elanco US Inc.; 2018. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.813 (2026-08-01). — Plumb's 10th ed (held) printed p.786, Lufenuron/Lufenuron Combination Products monograph spanning p.785-787; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Lufenuron is used in dogs for Flea prevention (IGR). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Lufenuron in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Program
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 10 mg/kg | q30d | Monthly with food | Flea prevention (IGR) | Strong | PROGRAM FLAVOR TABS - lufenuron tablet [US canine and feline product label]. In: Elanco US Inc.; 2018. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.813 (2026-08-01). — Plumb's 10th ed (held) printed p.786, Lufenuron/Lufenuron Combination Products monograph spanning p.785-787; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 10 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.255 | 10 mg/kg p.o., s.c. q1month (equivalent to a dose of 0.5 mg/kg milbemycin in combined preparations |
| 10 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.491 | • Flea control: 10 mg/kg q30d PO. |
| 80 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.491 | • Dermatophytes: 80 mg/kg, every 2 weeks, PO (efficacy questionable). |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Inhibits chitin synthesis in flea eggs and larvae, preventing development. Does not kill adult fleas.
Does NOT kill adult fleas — prevents flea egg development only. Must be used as part of comprehensive flea control. Give with food for absorption.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Lufenuron dose range in dogs, with cited source references: PO 10 mg/kg q30d. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Lufenuron in dogs: PO.
Cited course lengths for Lufenuron in dogs include: Monthly with food. Duration depends on the indication — match it to the specific dose rule in the table above.
Lufenuron is indicated in dogs for: Flea prevention (IGR).
These are general warnings for Lufenuron across species; consult the dog dosing table above for species-specific guidance. Does NOT kill adult fleas — prevents flea egg development only. Must be used as part of comprehensive flea control. Give with food for absorption.
Why a species-specific page? Lufenuron pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.