Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Fosfomycin is dosed at 40–80 mg/kg PO (with food) q12h in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (2023), Fosfomycin, p.587, DOGS row; superscript 1 = Weese JS, Blondeau J, Boothe D, et al. ISCAID guidelines for the diagnosis and management of bacterial urinary tract infections in dogs and cats. Vet J. 2019;247:8-25; superscript 14 = Harada K, Shimizu T, Kawaguchi K, Furuhashi T, Ishihara G. Urinary Pharmacokinetic and Pharmacodynamic Profiles of Fosfomycin against Extended-Spectrum β-Lactamase-Producing Escherichia coli with Canine Ex Vivo Modeling: A Pilot Study. Antibiotics. 2020;9(5):230. Fosfomycin is used in dogs for Resistant UTI. Routes documented in dogs: PO (with food). A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Fosfomycin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Monurol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO (with food) | 40–80 mg/kg | q12h | 7-14 days | Resistant UTI | Weak | Plumb's Veterinary Drug Handbook, 10th ed (2023), Fosfomycin, p.587, DOGS row; superscript 1 = Weese JS, Blondeau J, Boothe D, et al. ISCAID guidelines for the diagnosis and management of bacterial urinary tract infections in dogs and cats. Vet J. 2019;247:8-25; superscript 14 = Harada K, Shimizu T, Kawaguchi K, Furuhashi T, Ishihara G. Urinary Pharmacokinetic and Pharmacodynamic Profiles of Fosfomycin against Extended-Spectrum β-Lactamase-Producing Escherichia coli with Canine Ex Vivo Modeling: A Pilot Study. Antibiotics. 2020;9(5):230 |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits MurA enzyme (enolpyruvyl transferase) in early cell wall synthesis. Unique mechanism with no cross-resistance to other classes.
Limited veterinary data. May cause GI upset. Useful for MDR urinary tract infections. Oral form has limited bioavailability except in urinary tract.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Fosfomycin dose range in dogs, with cited source references: PO (with food) 40–80 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Fosfomycin in dogs: PO (with food).
Cited course lengths for Fosfomycin in dogs include: 7-14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Fosfomycin is indicated in dogs for: Resistant UTI.
These are general warnings for Fosfomycin across species; consult the dog dosing table above for species-specific guidance. Limited veterinary data. May cause GI upset. Useful for MDR urinary tract infections. Oral form has limited bioavailability except in urinary tract.
Why a species-specific page? Fosfomycin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.