Question 1

What is Fosfomycin used for?

Accepted Answer

Fosfomycin is indicated for: Resistant UTI.

Question 2

What routes can Fosfomycin be administered by?

Accepted Answer

Available routes: PO, IV.

Question 3

Which species have cited Fosfomycin dosing data?

Accepted Answer

Fosfomycin dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Fosfomycin a controlled substance?

Accepted Answer

Fosfomycin is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Fosfomycin?

Accepted Answer

Limited veterinary data. May cause GI upset. Useful for MDR urinary tract infections. Oral form has limited bioavailability except in urinary tract.

Question 6

What are the side effects of Fosfomycin?

Accepted Answer

Reported side effects, adverse reactions, and contraindications for Fosfomycin: Limited veterinary data. May cause GI upset. Useful for MDR urinary tract infections. Oral form has limited bioavailability except in urinary tract.

Question 7

How does Fosfomycin work?

Accepted Answer

Inhibits MurA enzyme (enolpyruvyl transferase) in early cell wall synthesis. Unique mechanism with no cross-resistance to other classes.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	PO	40–80 mg/kg	q8-12h	Weak	Plumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)	PO	40–80 mg/kg	q8-12h	Weak	Plumb's Veterinary Drug Handbook, 9th Ed

Fosfomycin

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Fosfomycin dosing data (2 dose rules)

Evidence levels across 2 dose rules

Backed by a published source

Sample dosing (2 of 2 cited rules)

Upgrade for Full Details