Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Silver Sulfadiazine is used in dogs for Surgical wound infection prevention, Burn wounds, skin ulcers, Burns and wound infections. Routes documented in dogs: TOPICAL, Topical. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 3 cited dose rules for Silver Sulfadiazine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: SSD Cream, Silvadene
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL | Apply to open/granulating wounds | q12-24h | Until epithelialization | Surgical wound infection prevention | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1460 (2026-08-01). |
| TOPICAL | Apply thin layer to wound | q12-24h | Until wound healed | Burn wounds, skin ulcers | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1460 (2026-08-01). |
| Topical | Apply 1/16 inch (~1.5 mm) layer to debrided wound | q12-24h | Until wound healed | Burns and wound infections | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1460 (2026-08-01). |
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Silver ions disrupt bacterial cell wall and membrane. Sulfadiazine inhibits folate synthesis. Broad antimicrobial activity against bacteria and some fungi.
For external use on wounds and burns only. May cause transient leukopenia with extensive application. Avoid in sulfonamide-allergic animals. Not for ophthalmic use.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Silver Sulfadiazine dose ranges in dogs, with cited source references: TOPICAL Apply to open/granulating wounds q12-24h; TOPICAL Apply thin layer to wound q12-24h; Topical Apply 1/16 inch (~1.5 mm) layer to debrided wound q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Silver Sulfadiazine in dogs: TOPICAL, Topical.
Cited course lengths for Silver Sulfadiazine in dogs include: Until epithelialization; Until wound healed. Duration depends on the indication — match it to the specific dose rule in the table above.
Silver Sulfadiazine is indicated in dogs for: Surgical wound infection prevention, Burn wounds, skin ulcers, Burns and wound infections.
These are general warnings for Silver Sulfadiazine across species; consult the dog dosing table above for species-specific guidance. For external use on wounds and burns only. May cause transient leukopenia with extensive application. Avoid in sulfonamide-allergic animals. Not for ophthalmic use.
Why a species-specific page? Silver Sulfadiazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.