Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Tylosin is dosed at 8–11 mg/kg IM q12h in dogs, per Papich Saunders Handbook of Veterinary Drugs 4th ed., Tylosin, Small Animal Dosage > Dogs, printed p.827 (corpus p.855). Tylosin is used in dogs for Susceptible infections, Chronic colitis, tylosin-responsive diarrhea. Routes documented in dogs: IM, PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Tylosin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Tylan
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 8–11 mg/kg | q12h | 7-14 days | Susceptible infections | Moderate | Papich Saunders Handbook of Veterinary Drugs 4th ed., Tylosin, Small Animal Dosage > Dogs, printed p.827 (corpus p.855) |
| PO | 5–15 mg/kg | q8-12h | Chronic (long-term) | Chronic colitis, tylosin-responsive diarrhea | Moderate | Simpson KW, Manchester A c. Chapter 134: Canine Colitis. In: Bonagura JD, Twedt DC, eds. Current Veterinary Therapy XV. Elsevier Saunders; 2014:550-553. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1312 (2026-08-01). |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds 50S ribosomal subunit, inhibiting bacterial protein synthesis. Anti-inflammatory properties in GI tract.
CONTRAINDICATED in rabbits, guinea pigs (fatal dysbiosis). Commonly used for chronic colitis in dogs. Very bitter taste. IM injection painful.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Tylosin dose ranges in dogs, with cited source references: IM 8–11 mg/kg q12h; PO 5–15 mg/kg q8-12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Tylosin in dogs: IM, PO.
Cited course lengths for Tylosin in dogs include: 7-14 days; Chronic (long-term). Duration depends on the indication — match it to the specific dose rule in the table above.
Tylosin is indicated in dogs for: Susceptible infections, Chronic colitis, tylosin-responsive diarrhea.
These are general warnings for Tylosin across species; consult the dog dosing table above for species-specific guidance. CONTRAINDICATED in rabbits, guinea pigs (fatal dysbiosis). Commonly used for chronic colitis in dogs. Very bitter taste. IM injection painful.
Why a species-specific page? Tylosin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.