Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Contraindicated in Horse (Equine)
Tylosin is dosed at 8–11 mg/kg IM q12h in dogs, per Papich Saunders Handbook of Veterinary Drugs 4th ed., Tylosin, Small Animal Dosage > Dogs, printed p.827. Tylosin is used in dogs for Susceptible infections, Adjunctive treatment of colitis (14 to 28 days, then maintain with 5 mg/kg PO q24h). Routes documented in dogs: IM, PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Tylosin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Tylan
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|
| IM | 8–11 mg/kg | q12h | 7-14 days | Susceptible infections | Weak | Papich Saunders Handbook of Veterinary Drugs 4th ed., Tylosin, Small Animal Dosage > Dogs, printed p.827Compilation only — we have not located an independent source that prints this figure. |
| PO | 5–15 mg/kg | q8h | Chronic (long-term) | Adjunctive treatment of colitis (14 to 28 days, then maintain with 5 mg/kg PO q24h) | Moderate | Simpson KW, Manchester A c. Chapter 134: Canine Colitis. In: Bonagura JD, Twedt DC, eds. Current Veterinary Therapy XV. Elsevier Saunders; 2014:550-553. — Plumb's 10th ed printed p.1284, Tylosin monograph spanning p.1284-1286.Compilation only — we have not located an independent source that prints this figure. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 7–15 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.436 | 7-15 mg/kg p.o. q12-24h. In colitis, higher doses recommended 12-20 mg/kg q8h with food gradua |
| 12–20 | — | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.436 | kg p.o. q12-24h. In colitis, higher doses recommended 12-20 mg/kg q8h with food gradually increasing the dosing interval to q24h |
| 7–15 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.855 | • 7-15 mg/kg q12-24h PO. |
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Binds 50S ribosomal subunit, inhibiting bacterial protein synthesis. Anti-inflammatory properties in GI tract.
CONTRAINDICATED in rabbits, guinea pigs (fatal dysbiosis). Commonly used for chronic colitis in dogs. Very bitter taste. IM injection painful.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Tylosin dose ranges in dogs, with cited source references: IM 8–11 mg/kg q12h; PO 5–15 mg/kg q8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Tylosin in dogs: IM, PO.
Cited course lengths for Tylosin in dogs include: 7-14 days; Chronic (long-term). Duration depends on the indication — match it to the specific dose rule in the table above.
Tylosin is indicated in dogs for: Susceptible infections, Adjunctive treatment of colitis (14 to 28 days, then maintain with 5 mg/kg PO q24h).
These are general warnings for Tylosin across species; consult the dog dosing table above for species-specific guidance. CONTRAINDICATED in rabbits, guinea pigs (fatal dysbiosis). Commonly used for chronic colitis in dogs. Very bitter taste. IM injection painful.
Why a species-specific page? Tylosin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 8–11 |
| IM |
| Papich Saunders Handbook of Veterinary Drugs, 4th edp.855 |
| • 8-11 mg/kg q12h IM. |
| 12–20 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.855 | • Colitis: 12-20 mg/kg q8h with food, then if there is a response, increase the interval |
| 20 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.855 | to q12h and eventually to q24h. (20 mg/kg is approximately 1/8 teaspoon of |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.