Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Tylosin is dosed at 17.6 mg/kg IM q24h in cattle, per FDA NADA 012-965 — TYLAN 200 (TYLOSIN) INJECTION, SOLUTION [ELANCO US INC.] — https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=510b4ec0-6762-4b29-9786-e5afa7350fa3 — label verbatim: "BEEF CATTLE AND NON-LACTATING DAIRY CATTLE— Inject intramuscularly 8 mg per pound of body weight […]" 8 mg/lb = 17.6 mg/kg. Corroborated: Plumb's 10th ed p.1313 CATTLE: "17.6 mg/kg IM once daily"; Papich p.855: "Cattle - Pododermatitis and pneumonia: 17.6 mg/kg q24h IM.". Tylosin is used in cattle for Bovine respiratory disease, foot rot, metritis. Routes documented in cattle: IM. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 1 cited dose rule for Tylosin in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Tylan
Contraindicated in Horse (Equine)
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 17.6 mg/kg | q24h | Continue 24 hours following remission of disease signs; not to exceed 5 days | Bovine respiratory disease, foot rot, metritis | Strong | FDA NADA 012-965 — TYLAN 200 (TYLOSIN) INJECTION, SOLUTION [ELANCO US INC.] — https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=510b4ec0-6762-4b29-9786-e5afa7350fa3 — label verbatim: "BEEF CATTLE AND NON-LACTATING DAIRY CATTLE— Inject intramuscularly 8 mg per pound of body weight […]" 8 mg/lb = 17.6 mg/kg. Corroborated: Plumb's 10th ed p.1313 CATTLE: "17.6 mg/kg IM once daily"; Papich p.855: "Cattle - Pododermatitis and pneumonia: 17.6 mg/kg q24h IM." |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (g/kg) | Route | Source | As printed |
|---|---|---|---|
| 22–220 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.855 | • Swine: Medicated feed dose is administered at a dose of 22-220 g/kg (of the pre- |
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 17.6 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.855 | • Pododermatitis and pneumonia: 17.6 mg/kg q24h IM. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Binds 50S ribosomal subunit, inhibiting bacterial protein synthesis. Anti-inflammatory properties in GI tract.
CONTRAINDICATED in rabbits, guinea pigs (fatal dysbiosis). Commonly used for chronic colitis in dogs. Very bitter taste. IM injection painful.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Tylosin dose range in cattle, with cited source references: IM 17.6 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Tylosin in cattle: IM.
Cited course lengths for Tylosin in cattle include: Continue 24 hours following remission of disease signs; not to exceed 5 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Tylosin is indicated in cattle for: Bovine respiratory disease, foot rot, metritis.
These are general warnings for Tylosin across species; consult the cattle dosing table above for species-specific guidance. CONTRAINDICATED in rabbits, guinea pigs (fatal dysbiosis). Commonly used for chronic colitis in dogs. Very bitter taste. IM injection painful.
Why a species-specific page? Tylosin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.