Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Cephapirin (Intramammary Dry Cow) is dosed at 200–300 mg per quarter INTRAMAMMARY q12h (lactating) or once (dry cow) in cattle, per TODAY INTRAMAMMARY INFUSION- Cephapirin Sodium Gel [US Product Label]. Boehringer Ingelheim Animal Health USA Inc.; 2020.; TOMORROW INTRAMAMMARY INFUSION- Cephapirin Benzathine Gel - US Product Label. Boehringer Ingelheim Vetmedica, Inc.; 2013. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.265 (2026-08-01).. Cephapirin (Intramammary Dry Cow) is used in cattle for Mastitis (lactating and dry cow), Dry cow mastitis therapy. Routes documented in cattle: INTRAMAMMARY. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 2 cited dose rules for Cephapirin (Intramammary Dry Cow) in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: ToDAY, ToMORROW
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| INTRAMAMMARY | 200–300 mg per quartermax 300 mg total | q12h (lactating) or once (dry cow) | 3 treatments (lactating); single (dry cow) | Mastitis (lactating and dry cow) | Strong | TODAY INTRAMAMMARY INFUSION- Cephapirin Sodium Gel [US Product Label]. Boehringer Ingelheim Animal Health USA Inc.; 2020.; TOMORROW INTRAMAMMARY INFUSION- Cephapirin Benzathine Gel - US Product Label. Boehringer Ingelheim Vetmedica, Inc.; 2013. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.265 (2026-08-01). |
| INTRAMAMMARY | 300 mg/quarter | single infusion per quarter at dry-off | — | Dry cow mastitis therapy | Strong | TOMORROW INTRAMAMMARY INFUSION- Cephapirin Benzathine Gel - US Product Label. Boehringer Ingelheim Vetmedica, Inc.; 2013. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.265 (2026-08-01). |
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First-generation cephalosporin that inhibits bacterial cell wall synthesis. Lactating and dry cow formulations provide local antimicrobial activity within the mammary gland.
For intramammary use in dairy cattle only. Lactating cow formulation: 96-hour milk withdrawal, 4-day meat withdrawal. Dry cow formulation: not for use within 30 days of calving.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cephapirin (Intramammary Dry Cow) dose ranges in cattle, with cited source references: INTRAMAMMARY 200–300 mg per quarter q12h (lactating) or once (dry cow); INTRAMAMMARY 300 mg/quarter single infusion per quarter at dry-off. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cephapirin (Intramammary Dry Cow) in cattle: INTRAMAMMARY.
Cited course lengths for Cephapirin (Intramammary Dry Cow) in cattle include: 3 treatments (lactating); single (dry cow). Duration depends on the indication — match it to the specific dose rule in the table above.
Cephapirin (Intramammary Dry Cow) is indicated in cattle for: Mastitis (lactating and dry cow), Dry cow mastitis therapy.
These are general warnings for Cephapirin (Intramammary Dry Cow) across species; consult the cattle dosing table above for species-specific guidance. For intramammary use in dairy cattle only. Lactating cow formulation: 96-hour milk withdrawal, 4-day meat withdrawal. Dry cow formulation: not for use within 30 days of calving.
Why a species-specific page? Cephapirin (Intramammary Dry Cow) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.