Cephapirin (Intramammary Dry Cow) for Cattle
Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Cephapirin (Intramammary Dry Cow) is used in cattle for Dry cow mastitis therapy, Mastitis (lactating and dry cow). Routes documented in cattle: INTRAMAMMARY. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 2 cited dose rules for Cephapirin (Intramammary Dry Cow) in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: ToDAY, ToMORROW
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| INTRAMAMMARY | 300 mg/quarter | single infusion per quarter at dry-off | — | Dry cow mastitis therapy | Strong | FDA NADA Label |
| INTRAMAMMARY | 200–300 mg per quarter | q12h (lactating) or once (dry cow) | 3 treatments (lactating); single (dry cow) | Mastitis (lactating and dry cow) | Strong | FDA NADA Label |
Absolute dose ceiling, regardless of body weight: 300 mg total (INTRAMAMMARY).
Need the exact dose for your patient?
These ranges are per kg. Enter your cattle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
First-generation cephalosporin that inhibits bacterial cell wall synthesis. Lactating and dry cow formulations provide local antimicrobial activity within the mammary gland.
Side effects & warnings
For intramammary use in dairy cattle only. Lactating cow formulation: 96-hour milk withdrawal, 4-day meat withdrawal. Dry cow formulation: not for use within 30 days of calving.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Antibiotic drugs with cattle dosing
Why a species-specific page? Cephapirin (Intramammary Dry Cow) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.