Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Cephapirin (Intramammary Dry Cow) is used in cattle for Dry cow mastitis therapy, Mastitis (lactating and dry cow). Routes documented in cattle: INTRAMAMMARY. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 2 cited dose rules for Cephapirin (Intramammary Dry Cow) in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: ToDAY, ToMORROW
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| INTRAMAMMARY | 300 mg/quarter | single infusion per quarter at dry-off | — | Dry cow mastitis therapy | Strong | FDA NADA Label |
| INTRAMAMMARY | 200–300 mg per quarter | q12h (lactating) or once (dry cow) | 3 treatments (lactating); single (dry cow) | Mastitis (lactating and dry cow) | Strong | FDA NADA Label |
Absolute dose ceiling, regardless of body weight: 300 mg total (INTRAMAMMARY).
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These ranges are per kg. Enter your cattle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
First-generation cephalosporin that inhibits bacterial cell wall synthesis. Lactating and dry cow formulations provide local antimicrobial activity within the mammary gland.
For intramammary use in dairy cattle only. Lactating cow formulation: 96-hour milk withdrawal, 4-day meat withdrawal. Dry cow formulation: not for use within 30 days of calving.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Cephapirin (Intramammary Dry Cow) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.