Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Cefquinome (Livestock) is dosed at 1–2 mg/kg IM q24h in cattle, per Cobactan® (Cefquinome) 25 Mg/Ml Suspension for Injection [Product Label]. MSD Animal Health; 2016. — Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.162 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.162' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.134; verified by finding the drug named there. If you are holding the book, turn to p.134. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855. Cefquinome (Livestock) is used in cattle for BRD, E. coli septicemia in calves, Bovine respiratory disease, Bovine mastitis (E. coli, Klebsiella). Routes documented in cattle: IM, INTRAMAMMARY. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 3 cited dose rules for Cefquinome (Livestock) in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Cobactan
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 1–2 mg/kg | q24h | 3-5 days | BRD, E. coli septicemia in calves | Moderate | Cobactan® (Cefquinome) 25 Mg/Ml Suspension for Injection [Product Label]. MSD Animal Health; 2016. — Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.162 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.162' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.134; verified by finding the drug named there. If you are holding the book, turn to p.134. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
| IM | 1 mg/kg | q24h for 2 to 5 consecutive days | 3-5 days | Bovine respiratory disease | Moderate | Cobactan (Cefquinome) 25 Mg/Ml Suspension for Injection [Product Label]. MSD Animal Health; 2016. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.245 (2026-08-01). — Plumb's 10th ed (held) printed p.218, Cefquinome monograph spanning p.216-218; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| INTRAMAMMARY | 75 mg per quartermax 75 mg total | q24h | 3 treatments | Bovine mastitis (E. coli, Klebsiella) | Moderate | Cobactan® (Cefquinome) LC [New Zealand Product Label]. Schering-Plough Animal Health Ltd; 2019. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.245 (2026-08-01). — Plumb's 10th ed (held) printed p.216, Cefquinome monograph spanning p.216-218; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Need the exact dose for your patient?
These ranges are per kg. Enter your cattle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Fourth-generation cephalosporin with broad-spectrum activity including many beta-lactamase-producing organisms. Stable against AmpC and extended-spectrum beta-lactamases.
For cattle and swine. Not approved in US (available in EU). Intramammary formulation for bovine mastitis. Concerns about ESBL resistance selection limit use in some jurisdictions.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cefquinome (Livestock) dose ranges in cattle, with cited source references: IM 1–2 mg/kg q24h; IM 1 mg/kg q24h for 2 to 5 consecutive days; INTRAMAMMARY 75 mg per quarter q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cefquinome (Livestock) in cattle: IM, INTRAMAMMARY.
Cited course lengths for Cefquinome (Livestock) in cattle include: 3-5 days; 3 treatments. Duration depends on the indication — match it to the specific dose rule in the table above.
Cefquinome (Livestock) is indicated in cattle for: BRD, E. coli septicemia in calves, Bovine respiratory disease, Bovine mastitis (E. coli, Klebsiella).
These are general warnings for Cefquinome (Livestock) across species; consult the cattle dosing table above for species-specific guidance. For cattle and swine. Not approved in US (available in EU). Intramammary formulation for bovine mastitis. Concerns about ESBL resistance selection limit use in some jurisdictions.
Why a species-specific page? Cefquinome (Livestock) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.