Cefquinome (Livestock) for Cattle
Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Cefquinome (Livestock) is used in cattle for Bovine respiratory disease, BRD, E. coli septicemia in calves, Bovine mastitis (E. coli, Klebsiella). Routes documented in cattle: IM, INTRAMAMMARY. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 3 cited dose rules for Cefquinome (Livestock) in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Cobactan
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 1 mg/kg | q24h | 3-5 days | Bovine respiratory disease | Moderate | Merck Veterinary Manual |
| IM | 1–2 mg/kg | q24h | 3-5 days | BRD, E. coli septicemia in calves | Moderate | Merck Veterinary Manual |
| INTRAMAMMARY | 75 mg per quarter | q24h | 3 treatments | Bovine mastitis (E. coli, Klebsiella) | Moderate | Merck Veterinary Manual |
Absolute dose ceiling, regardless of body weight: 75 mg total (INTRAMAMMARY).
Need the exact dose for your patient?
These ranges are per kg. Enter your cattle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Fourth-generation cephalosporin with broad-spectrum activity including many beta-lactamase-producing organisms. Stable against AmpC and extended-spectrum beta-lactamases.
Side effects & warnings
For cattle and swine. Not approved in US (available in EU). Intramammary formulation for bovine mastitis. Concerns about ESBL resistance selection limit use in some jurisdictions.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Antibiotic drugs with cattle dosing
Cefquinome (Livestock) dosing in other species
Why a species-specific page? Cefquinome (Livestock) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.