Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Erythromycin is dosed at 4.4–8.8 mg/kg IM q24h in cattle, per Gallimycin-100 Injection [product label]. LettSueur, MN: Bimeda-MTC Animal Health. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.503 (2026-08-01). — Plumb's 10th ed (held) printed p.473, Erythromycin monograph spanning p.473-476; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — 21 CFR § 522.820 (Erythromycin), conditions of use for Cattle: 8.8185-8.8185 mg/kg (the regulation prints this per pound; converted at 2.2046226 lb/kg). Related tolerances: 21 CFR § 556.230. Retrieved from the eCFR API, snapshot 2026-01-01. https://www.ecfr.gov/current/title-21/section-522.820 — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Erythromycin is used in cattle for Respiratory infection. Routes documented in cattle: IM. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 1 cited dose rule for Erythromycin in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Erythro-100, Gallimycin
Contraindicated in Chinchilla, Guinea Pig, Rabbit, Hamster, Degu
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 4.4–8.8 mg/kg | q24h | 3-5 days | Respiratory infection | Moderate | Gallimycin-100 Injection [product label]. LettSueur, MN: Bimeda-MTC Animal Health. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.503 (2026-08-01). — Plumb's 10th ed (held) printed p.473, Erythromycin monograph spanning p.473-476; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — 21 CFR § 522.820 (Erythromycin), conditions of use for Cattle: 8.8185-8.8185 mg/kg (the regulation prints this per pound; converted at 2.2046226 lb/kg). Related tolerances: 21 CFR § 556.230. Retrieved from the eCFR API, snapshot 2026-01-01. https://www.ecfr.gov/current/title-21/section-522.820 — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 2.2–8.8 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.327 | • Pneumonia: 2.2-8.8 mg/kg q24h IM or 15 mg/kg q12h IM. |
| 15 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.327 | • Pneumonia: 2.2-8.8 mg/kg q24h IM or 15 mg/kg q12h IM. |
| 8.8 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.327 | • Stimulate rumen motility: calves 8.8 mg/kg IM; cows 10 mg/kg IM. |
| 10 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.327 | • Stimulate rumen motility: calves 8.8 mg/kg IM; cows 10 mg/kg IM. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Binds 50S ribosomal subunit, inhibiting translocation of peptidyl-tRNA, blocking bacterial protein synthesis.
CONTRAINDICATED in rabbits and hindgut fermenters. Prokinetic at sub-antimicrobial doses. GI upset common. Hepatotoxicity reported. Strong CYP inhibitor.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Erythromycin dose range in cattle, with cited source references: IM 4.4–8.8 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Erythromycin in cattle: IM.
Cited course lengths for Erythromycin in cattle include: 3-5 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Erythromycin is indicated in cattle for: Respiratory infection.
These are general warnings for Erythromycin across species; consult the cattle dosing table above for species-specific guidance. CONTRAINDICATED in rabbits and hindgut fermenters. Prokinetic at sub-antimicrobial doses. GI upset common. Hepatotoxicity reported. Strong CYP inhibitor.
Why a species-specific page? Erythromycin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.