Question 1

What is Tylosin used for?

Accepted Answer

Tylosin is indicated for: air sacculitis, arthritis, Bovine respiratory disease, Chronic colitis, Chronic respiratory disease (CRD), Chronic respiratory disease (mycoplasma), foot rot, infectious sinusitis, metritis, Mycoplasma, pneumonia, Susceptible infections, Swine dysentery, tylosin-responsive diarrhea.

Question 2

What routes can Tylosin be administered by?

Accepted Answer

Available routes: PO, IM.

Question 3

Which species have cited Tylosin dosing data?

Accepted Answer

Tylosin dosing in the ExoticRx formulary covers 6 species: African Grey Parrot, Cattle (Beef/Dairy), Chicken (Poultry), Dog (Domestic), Swine (Pig), Turkey.

Question 4

Is Tylosin a controlled substance?

Accepted Answer

Tylosin is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Tylosin?

Accepted Answer

CONTRAINDICATED in rabbits, guinea pigs (fatal dysbiosis). Commonly used for chronic colitis in dogs. Very bitter taste. IM injection painful.

Question 6

What are the side effects of Tylosin?

Accepted Answer

Reported side effects, adverse reactions, and contraindications for Tylosin: CONTRAINDICATED in rabbits, guinea pigs (fatal dysbiosis). Commonly used for chronic colitis in dogs. Very bitter taste. IM injection painful.

Question 7

How does Tylosin work?

Accepted Answer

Binds 50S ribosomal subunit, inhibiting bacterial protein synthesis. Anti-inflammatory properties in GI tract.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	IM	5–10 mg/kg	q12-24h	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed
Dog (Domestic)	PO	5–15 mg/kg	q8-12h	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed

Tylosin

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Tylosin dosing data (8 dose rules)

Evidence levels across 8 dose rules

Backed by 3 published sources

Sample dosing (2 of 8 cited rules)

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