Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Propofol Constant Rate Infusion is dosed at 0.1–0.4 mg/kg/min IV CRI after induction bolus (4-6mg/kg) in dogs, per Grimm KA, Lamont LA, Tranquilli WJ, Greene SA, Robertson SA. Veterinary Anesthesia and Analgesia: The Fifth Edition of Lumb and Jones. 5th ed. Wiley-Blackwell; 2015. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1111 (2026-08-01).. Propofol Constant Rate Infusion is used in dogs for Total IV anesthesia (TIVA). Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Propofol Constant Rate Infusion in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: PropoFlo CRI
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.1–0.4 mg/kg/min | CRI after induction bolus (4-6mg/kg) | Duration of procedure; rapid recovery after discontinuation | Total IV anesthesia (TIVA) | Strong | Grimm KA, Lamont LA, Tranquilli WJ, Greene SA, Robertson SA. Veterinary Anesthesia and Analgesia: The Fifth Edition of Lumb and Jones. 5th ed. Wiley-Blackwell; 2015. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1111 (2026-08-01). |
One of the cited rules is a continuous-rate-infusion regimen: IV 0.1–0.4 mg/kg/min CRI after induction bolus (4-6mg/kg). CRI regimens are delivered as a continuous infusion rather than discrete doses — verify the rate against the cited source before use.
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
GABA-A receptor agonist providing continuous plane of anesthesia without accumulation during prolonged procedures. Rapid onset and recovery.
Heinz body anemia in cats with repeated daily use (>3 days). Hypotension and apnea common. Strict aseptic technique — lipid emulsion supports bacterial growth.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Propofol Constant Rate Infusion dose range in dogs, with cited source references: IV 0.1–0.4 mg/kg/min CRI after induction bolus (4-6mg/kg). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Propofol Constant Rate Infusion in dogs: IV.
Cited course lengths for Propofol Constant Rate Infusion in dogs include: Duration of procedure; rapid recovery after discontinuation. Duration depends on the indication — match it to the specific dose rule in the table above.
Propofol Constant Rate Infusion is indicated in dogs for: Total IV anesthesia (TIVA).
These are general warnings for Propofol Constant Rate Infusion across species; consult the dog dosing table above for species-specific guidance. Heinz body anemia in cats with repeated daily use (>3 days). Hypotension and apnea common. Strict aseptic technique — lipid emulsion supports bacterial growth.
Why a species-specific page? Propofol Constant Rate Infusion pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.