Cat · Felis catus · typical adult weight 2.50–7.00 kg
Propofol Constant Rate Infusion is dosed at 0.1–0.3 mg/kg/min IV CRI after induction bolus (4-8mg/kg) in cats, per Campagna I, Schwarz A, Keller S, Bettschart-Wolfensberger R, Mosing M. Comparison of the effects of propofol or alfaxalone for anaesthesia induction and maintenance on respiration in cats. Vet Anaesth Analg. 2015;42(5):484-492. doi:10.1111/vaa.12231 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1111 (2026-08-01). — Plumb's 10th ed (held) printed p.1080, Propofol monograph spanning p.1080-1085; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Propofol Constant Rate Infusion is used in cats for Total IV anesthesia/Short procedure maintenance. Routes documented in cats: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Propofol Constant Rate Infusion in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: PropoFlo CRI
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.1–0.3 mg/kg/min | CRI after induction bolus (4-8mg/kg) | Short procedures only in cats; avoid daily repeated use (Heinz body anemia) | Total IV anesthesia/Short procedure maintenance | Strong | Campagna I, Schwarz A, Keller S, Bettschart-Wolfensberger R, Mosing M. Comparison of the effects of propofol or alfaxalone for anaesthesia induction and maintenance on respiration in cats. Vet Anaesth Analg. 2015;42(5):484-492. doi:10.1111/vaa.12231 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1111 (2026-08-01). — Plumb's 10th ed (held) printed p.1080, Propofol monograph spanning p.1080-1085; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (%) | Route | Source | As printed |
|---|---|---|---|
| 24 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | sedatives are used, reduce by 16%-24%. If combined with midazolam, the propo- |
| 16 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | sedatives are used, reduce by 16%-24%. If combined with midazolam, the propo- |
| 25 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | fol requirement listed can be reduced by as much as 25%. |
One of the cited rules is a continuous-rate-infusion regimen: IV 0.1–0.3 mg/kg/min CRI after induction bolus (4-8mg/kg). CRI regimens are delivered as a continuous infusion rather than discrete doses — verify the rate against the cited source before use.
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
GABA-A receptor agonist providing continuous plane of anesthesia without accumulation during prolonged procedures. Rapid onset and recovery.
Heinz body anemia in cats with repeated daily use (>3 days). Hypotension and apnea common. Strict aseptic technique — lipid emulsion supports bacterial growth.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Propofol Constant Rate Infusion dose range in cats, with cited source references: IV 0.1–0.3 mg/kg/min CRI after induction bolus (4-8mg/kg). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Propofol Constant Rate Infusion in cats: IV.
Cited course lengths for Propofol Constant Rate Infusion in cats include: Short procedures only in cats; avoid daily repeated use (Heinz body anemia). Duration depends on the indication — match it to the specific dose rule in the table above.
Propofol Constant Rate Infusion is indicated in cats for: Total IV anesthesia/Short procedure maintenance.
These are general warnings for Propofol Constant Rate Infusion across species; consult the cat dosing table above for species-specific guidance. Heinz body anemia in cats with repeated daily use (>3 days). Hypotension and apnea common. Strict aseptic technique — lipid emulsion supports bacterial growth.
Why a species-specific page? Propofol Constant Rate Infusion pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| Dose (mcg/kg) | Route | Source | As printed |
|---|
| 200–300 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | • CRI: 6 mg/kg slowly IV, followed by 200-300 mcg/kg/min (0.2-0.3 mg/kg) IV. |
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 8 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.363 | 8 mg/kg i.v.; premedicated 2-5 mg/kg i.v. 348 BSAVA Small Animal Formulary 10th edition: Part |
| 2–5 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.363 | 8 mg/kg i.v.; premedicated 2-5 mg/kg i.v. 348 BSAVA Small Animal Formulary 10th edition: Part A - Canine and Feline |
| 15 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | For short-term procedures the total dose is 15 mg/kg for 30-minute protocol. |
| 10 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | • Short-term surgery: 10 mg/kg IV dose delivered over 1 minute (duration of |
| 0.2–0.3 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | • CRI: 6 mg/kg slowly IV, followed by 200-300 mcg/kg/min (0.2-0.3 mg/kg) IV. |
| 6 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | • CRI: 6 mg/kg slowly IV, followed by 200-300 mcg/kg/min (0.2-0.3 mg/kg) IV. |
| 1–3 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | of 1-3 mg/kg IV can be administered as needed. If other preanesthetics and |
| 4–8 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | • Anesthesia induction: 4-8 mg/kg IV slowly. After initial dose, incremental doses |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.