Dantrolene Injectable for Cat
Cat · Felis catus · typical adult weight 2.50–7.00 kg
Dantrolene Injectable is used in cat for Malignant hyperthermia. Routes documented in cat: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Dantrolene Injectable in cat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Dantrium IV, Ryanodex
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 1–3.5 mg/kg | IV push; repeat as needed | Repeat until signs resolve; max 10mg/kg total | Malignant hyperthermia | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Directly inhibits calcium release from the sarcoplasmic reticulum by blocking ryanodine receptors, preventing excitation-contraction coupling in skeletal muscle.
Side effects & warnings
Primary treatment for malignant hyperthermia. Mix requires warming and vigorous shaking. Hepatotoxic with chronic oral use. Muscle weakness expected effect.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Miscellaneous drugs with cat dosing
Dantrolene Injectable dosing in other species
Why a species-specific page? Dantrolene Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.