Cat · Felis catus · typical adult weight 2.50–7.00 kg
Mannitol 20% Injectable is dosed at 500–1000 mg/kg IV Over 15-20 min in cats, per DiFazio J, Fletcher DJ. Updates in the Management of the Small Animal Patient with Neurologic Trauma. Vet Clin North Am Small Anim Pract. 2013;43(4):915-940. doi:10.1016/j.cvsm.2013.03.002; Pigott A, Rudloff E. Traumatic Brain Injury-A Review of Intravenous Fluid Therapy. Front Vet Sci. 2021;8:643800. doi:10.3389/fvets.2021.643800 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.822 (2026-08-01).. Mannitol 20% Injectable is used in cats for Acute glaucoma. Routes documented in cats: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Mannitol 20% Injectable in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Osmitrol 20%
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 500–1000 mg/kg | Over 15-20 min | Single dose for acute IOP reduction while preparing for definitive treatment | Acute glaucoma |
| Moderate |
| DiFazio J, Fletcher DJ. Updates in the Management of the Small Animal Patient with Neurologic Trauma. Vet Clin North Am Small Anim Pract. 2013;43(4):915-940. doi:10.1016/j.cvsm.2013.03.002; Pigott A, Rudloff E. Traumatic Brain Injury-A Review of Intravenous Fluid Therapy. Front Vet Sci. 2021;8:643800. doi:10.3389/fvets.2021.643800 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.822 (2026-08-01). |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Osmotically active sugar alcohol that increases plasma osmolality, drawing fluid from brain and ocular tissues. Also promotes osmotic diuresis in renal tubules.
For acute head trauma/glaucoma emergencies. Crystallizes at low temperature — warm and use in-line filter. Contraindicated in anuric renal failure and pulmonary edema.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Mannitol 20% Injectable dose range in cats, with cited source references: IV 500–1000 mg/kg Over 15-20 min. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Mannitol 20% Injectable in cats: IV.
Cited course lengths for Mannitol 20% Injectable in cats include: Single dose for acute IOP reduction while preparing for definitive treatment. Duration depends on the indication — match it to the specific dose rule in the table above.
Mannitol 20% Injectable is indicated in cats for: Acute glaucoma.
These are general warnings for Mannitol 20% Injectable across species; consult the cat dosing table above for species-specific guidance. For acute head trauma/glaucoma emergencies. Crystallizes at low temperature — warm and use in-line filter. Contraindicated in anuric renal failure and pulmonary edema.
Why a species-specific page? Mannitol 20% Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.