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Mannitol 20% Injectable for Cat

Cat · Felis catus · typical adult weight 2.50–7.00 kg

Mannitol 20% Injectable is used in cat for Acute glaucoma. Routes documented in cat: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Mannitol 20% Injectable in cat, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Osmitrol 20%

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
IV500–1000 mg/kgOver 15-20 minSingle dose for acute IOP reduction while preparing for definitive treatmentAcute glaucomaModeratePlumb's Veterinary Drug Handbook, 9th Ed

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Mechanism of action

Osmotically active sugar alcohol that increases plasma osmolality, drawing fluid from brain and ocular tissues. Also promotes osmotic diuresis in renal tubules.

Side effects & warnings

For acute head trauma/glaucoma emergencies. Crystallizes at low temperature — warm and use in-line filter. Contraindicated in anuric renal failure and pulmonary edema.

Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Miscellaneous drugs with cat dosing

Mannitol 20% Injectable dosing in other species

Why a species-specific page? Mannitol 20% Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.