Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Dantrolene Injectable is dosed at 1–3.5 mg/kg IV IV push; may repeat q5-10min up to 10mg/kg total in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed; Veterinary Anesthesia Textbooks. Dantrolene Injectable is used in dogs for Malignant hyperthermia. Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Dantrolene Injectable in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Dantrium IV, Ryanodex
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 1–3.5 mg/kg | IV push; may repeat q5-10min up to 10mg/kg total | Repeat until muscle rigidity resolves or max dose; follow with oral for 24-48h | Malignant hyperthermia | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed; Veterinary Anesthesia Textbooks |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Directly inhibits calcium release from the sarcoplasmic reticulum by blocking ryanodine receptors, preventing excitation-contraction coupling in skeletal muscle.
Primary treatment for malignant hyperthermia. Mix requires warming and vigorous shaking. Hepatotoxic with chronic oral use. Muscle weakness expected effect.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Dantrolene Injectable dose range in dogs, with cited source references: IV 1–3.5 mg/kg IV push; may repeat q5-10min up to 10mg/kg total. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Dantrolene Injectable in dogs: IV.
Cited course lengths for Dantrolene Injectable in dogs include: Repeat until muscle rigidity resolves or max dose; follow with oral for 24-48h. Duration depends on the indication — match it to the specific dose rule in the table above.
Dantrolene Injectable is indicated in dogs for: Malignant hyperthermia.
These are general warnings for Dantrolene Injectable across species; consult the dog dosing table above for species-specific guidance. Primary treatment for malignant hyperthermia. Mix requires warming and vigorous shaking. Hepatotoxic with chronic oral use. Muscle weakness expected effect.
Why a species-specific page? Dantrolene Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.