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Dextrose 50% for Dog

Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg

Dextrose 50% is used in dog for Hypoglycemia. Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Dextrose 50% in dog, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: D50W

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
IV0.25–0.5 g/kgBolus, then CRI 2.5-5% dextrose in fluidsUntil blood glucose stabilizedHypoglycemiaStrongPlumb's Veterinary Drug Handbook, 9th Ed

Continuous-rate infusion (CRI) in dog

One of the cited rules is a continuous-rate-infusion regimen: IV 0.25–0.5 g/kg Bolus, then CRI 2.5-5% dextrose in fluids. CRI regimens are delivered as a continuous infusion rather than discrete doses — verify the rate against the cited source before use.

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Mechanism of action

Provides glucose for cellular energy metabolism. Corrects hypoglycemia and provides caloric support.

Side effects & warnings

Must dilute to 10-12.5% for peripheral IV (phlebitis risk). Hyperglycemia with excessive dosing. Monitor blood glucose frequently.

Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Miscellaneous drugs with dog dosing

Dextrose 50% dosing in other species

Why a species-specific page? Dextrose 50% pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.