Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Dextrose 50% is dosed at 0.25–0.5 g/kg IV Bolus, then CRI 2.5-5% dextrose in fluids in dogs, per Koenig A. Hypoglycemia. In: Silverstein D, Hopper K, eds. Small Animal Critical Care Medicie. St. Lous: Elsevier Saunders; 2008:295-297. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.404 (2026-08-01).. Dextrose 50% is used in dogs for Hypoglycemia. Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Dextrose 50% in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: D50W
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.25–0.5 g/kg | Bolus, then CRI 2.5-5% dextrose in fluids | Until blood glucose stabilized | Hypoglycemia | Strong | Koenig A. Hypoglycemia. In: Silverstein D, Hopper K, eds. Small Animal Critical Care Medicie. St. Lous: Elsevier Saunders; 2008:295-297. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.404 (2026-08-01). |
One of the cited rules is a continuous-rate-infusion regimen: IV 0.25–0.5 g/kg Bolus, then CRI 2.5-5% dextrose in fluids. CRI regimens are delivered as a continuous infusion rather than discrete doses — verify the rate against the cited source before use.
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Provides glucose for cellular energy metabolism. Corrects hypoglycemia and provides caloric support.
Must dilute to 10-12.5% for peripheral IV (phlebitis risk). Hyperglycemia with excessive dosing. Monitor blood glucose frequently.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Dextrose 50% dose range in dogs, with cited source references: IV 0.25–0.5 g/kg Bolus, then CRI 2.5-5% dextrose in fluids. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Dextrose 50% in dogs: IV.
Cited course lengths for Dextrose 50% in dogs include: Until blood glucose stabilized. Duration depends on the indication — match it to the specific dose rule in the table above.
Dextrose 50% is indicated in dogs for: Hypoglycemia.
These are general warnings for Dextrose 50% across species; consult the dog dosing table above for species-specific guidance. Must dilute to 10-12.5% for peripheral IV (phlebitis risk). Hyperglycemia with excessive dosing. Monitor blood glucose frequently.
Why a species-specific page? Dextrose 50% pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.