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Dextrose 50%

D50W

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Miscellaneous

Routes

IV

Indications

Mechanism of Action

Provides glucose for cellular energy metabolism. Corrects hypoglycemia and provides caloric support.

Side effects & warnings

Must dilute to 10-12.5% for peripheral IV (phlebitis risk). Hyperglycemia with excessive dosing. Monitor blood glucose frequently.

Species with Dextrose 50% dosing data (2 dose rules)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Constant rate infusion (CRI)

Dextrose 50% CRI dose rules from the ExoticRx formulary. Verify against current literature before clinical use; CRI rates differ from bolus dosing and route, dilution, and monitoring matter. Sign in for the complete per-species CRI protocol set.

  • Dog (Domestic)IV
    0.25–0.5 g/kgBolus, then CRI 2.5-5% dextrose in fluids

    Hypoglycemia

    StrongPlumb's Veterinary Drug Handbook, 9th Ed
  • Cat (Domestic)IV
    0.25–0.5 g/kgBolus, then CRI

    Hypoglycemia

    StrongPlumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)IV0.25–0.5 g/kgBolus, then CRI 2.5-5% dextrose in fluidsStrongPlumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)IV0.25–0.5 g/kgBolus, then CRIStrongPlumb's Veterinary Drug Handbook, 9th Ed

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