ExoticRx · exoticrx.com/drugs/dextrose-50
US brand names:D50W
Dextrose 50% is dosed at 0.25–0.5 g/kg IV Bolus, then CRI 2.5-5% dextrose in fluids in dogs, per Koenig A. Hypoglycemia. In: Silverstein D, Hopper K, eds. Small Animal Critical Care Medicie. St. Lous: Elsevier Saunders; 2008:295-297. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.404 (2026-08-01).. Verify against current literature before clinical use.
Provides glucose for cellular energy metabolism. Corrects hypoglycemia and provides caloric support.
Must dilute to 10-12.5% for peripheral IV (phlebitis risk). Hyperglycemia with excessive dosing. Monitor blood glucose frequently.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Dextrose 50% CRI dose rules from the ExoticRx formulary. Verify against current literature before clinical use; CRI rates differ from bolus dosing and route, dilution, and monitoring matter. Sign in for the complete per-species CRI protocol set.
| Species | Route | Rate | Indication | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.25–0.5 g/kgBolus, then CRI 2.5-5% dextrose in fluids | Hypoglycemia | Strong | Koenig A. Hypoglycemia. In: Silverstein D, Hopper K, eds. Small Animal Critical Care Medicie. St. Lous: Elsevier Saunders; 2008:295-297. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.404 (2026-08-01). |
| Cat (Domestic) | IV | 0.25–0.5 g/kgBolus, then CRI | Hypoglycemia | Strong | Koenig A. Hypoglycemia. In: Silverstein D, Hopper K, eds. Small Animal Critical Care Medicie. St. Lous: Elsevier Saunders; 2008:295-297. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.404 (2026-08-01). |
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.25–0.5 g/kg | Bolus, then CRI 2.5-5% dextrose in fluids | Strong | Koenig A. Hypoglycemia. In: Silverstein D, Hopper K, eds. Small Animal Critical Care Medicie. St. Lous: Elsevier Saunders; 2008:295-297. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.404 (2026-08-01). |
| Cat (Domestic) | IV | 0.25–0.5 g/kg | Bolus, then CRI | Strong | Koenig A. Hypoglycemia. In: Silverstein D, Hopper K, eds. Small Animal Critical Care Medicie. St. Lous: Elsevier Saunders; 2008:295-297. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.404 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.
Hypoglycemia
Hypoglycemia