Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Apomorphine is used in dog for Emesis induction (conjunctival route), Emesis induction (in-clinic). Routes documented in dog: Conjunctival, IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Apomorphine in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Apoquel Emetic
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Conjunctival | 0.25 mg/kg | Single application; flush eye once vomiting begins | Single use; rinse eye thoroughly with saline after emesis induced | Emesis induction (conjunctival route) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| IV | 0.03–0.04 mg/kg | Single IV dose | Single dose; onset within 2-5 minutes IV; do NOT repeat if ineffective | Emesis induction (in-clinic) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed; ASPCA Toxicology |
Absolute dose ceiling, regardless of body weight: 6 mg total (Conjunctival).
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Dopamine D2 receptor agonist in the chemoreceptor trigger zone (CRTZ), directly stimulating the vomiting center. Most reliable emetic for dogs.
Dogs ONLY — cats lack appropriate CRTZ dopamine receptors (use dexmedetomidine instead). Respiratory depression at high doses. Naloxone can reverse. Do NOT repeat if first dose fails.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Apomorphine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.