Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Misoprostol Veterinary is used in dog for NSAID-induced GI ulcer prophylaxis, GI ulcer treatment. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Misoprostol Veterinary in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Cytotec Vet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.002–0.005 mg/kg | q8-12h | Duration of NSAID therapy; continue 2-3 days after NSAID discontinuation | NSAID-induced GI ulcer prophylaxis | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 0.003–0.005 mg/kg | q8h | 4-8 weeks for ulcer healing; combine with sucralfate and PPI | GI ulcer treatment | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed; ACVIM GI Position Statement |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Synthetic prostaglandin E1 analog that replaces protective prostaglandins depleted by NSAIDs. Stimulates mucus and bicarbonate secretion and maintains mucosal blood flow.
ABORTIFACIENT — do not handle if pregnant. Diarrhea common initially. Co-prescribe with chronic NSAID use for GI protection. Do not use in pregnant animals.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Misoprostol Veterinary pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.