Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Morphine is used in dog for Surgical analgesia (hindlimb, perineal), Moderate to severe pain, Severe pain, CRI. Routes documented in dog: EPIDURAL, IM, IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 3 cited dose rules for Morphine in dog, drawn from published veterinary references. Verify against current literature before clinical use.
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| EPIDURAL | 0.1 mg/kg | Single injection | Single epidural dose (up to 24h effect) | Surgical analgesia (hindlimb, perineal) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| IM | 0.5–2 mg/kg | q4-6h | Short-term | Moderate to severe pain | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| IV | 0.1–0.5 mg/kg | q2-4h bolus or 0.1-0.3 mg/kg/h CRI | Short-term | Severe pain, CRI | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
One of the cited rules is a continuous-rate-infusion regimen: IV 0.1–0.5 mg/kg q2-4h bolus or 0.1-0.3 mg/kg/h CRI. CRI regimens are delivered as a continuous infusion rather than discrete doses — verify the rate against the cited source before use.
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Prototype full mu-opioid receptor agonist. Activates mu, kappa, and delta opioid receptors producing analgesia, sedation, and euphoria.
Histamine release with rapid IV injection (hypotension, bronchoconstriction — give slowly). Vomiting and defecation common initial effects. Respiratory depression. Cats: may cause excitation/dysphoria at higher doses. Controlled substance (Schedule II).
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Morphine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.