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Butorphanol for Dog

Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg

Butorphanol is used in dog for Pre-anesthetic sedation, visceral pain, Visceral pain, sedation adjunct, pre-anesthetic, Antitussive, Mild visceral pain. Routes documented in dog: IM, IV, SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 4 cited dose rules for Butorphanol in dog, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Torbugesic, Torbutrol

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
IM0.2–0.4 mg/kgq2-4hAs neededPre-anesthetic sedation, visceral painStrongPlumb's Veterinary Drug Handbook, 9th Ed
IV0.1–0.4 mg/kgq2-4hShort duration — repeat as neededVisceral pain, sedation adjunct, pre-anestheticStrongPlumb's Veterinary Drug Handbook, 9th Ed
IV0.05–0.1 mg/kgq6-12hAs neededAntitussiveModeratePlumb's Veterinary Drug Handbook, 9th Ed
SC0.2–0.4 mg/kgq2-4hAs neededMild visceral painStrongPlumb's Veterinary Drug Handbook, 9th Ed

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Mechanism of action

Kappa-opioid receptor agonist and mu-opioid receptor antagonist. Provides visceral analgesia and sedation.

Side effects & warnings

Short duration of action (1-2 hours). Better for visceral than somatic pain. Ceiling effect on analgesia. May cause sedation and mild respiratory depression.

Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Analgesic drugs with dog dosing

Butorphanol dosing in other species

Why a species-specific page? Butorphanol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.